Geriatric Division, Department of Clinical and Biological Sciences, San Luigi Gonzaga Hospital, University of Turin, Regione Gonzole 10, 10043, Orbassano (Turin), Italy.
Aging Clin Exp Res. 2013 Dec;25(6):633-6. doi: 10.1007/s40520-013-0162-2. Epub 2013 Oct 23.
Frailty is a common situation that often influences clinical outcomes, disability or institutionalization. The present study aims to evaluate the weight of hand grip strength (HGS) reduction in terms of death or re-hospitalizations, at 3-month and 1-year follow-up.
Observational study performed on hospitalized patients aged 65 years or more. The HGS was measured twice: at hospital admission and discharge. The statistical analysis was performed using SPSS, version 18 for Windows. The χ (2) test was used to evaluate the relationship between HGS and different variables. Three-month and 1-year survival and hospital re-admissions have been analyzed using Kaplan-Meier's curves. The analyses have been adjusted for age and gender.
A total of 201 hospitalized patients have been recruited. Of them, 76 were males. The mean age was 81.79 ± 7.409 years. Of all the patients enrolled, 66.2 and 45.3 % did not show any impairment performing activities of daily living and instrumental activities of daily living, respectively. Moreover, patients were not cognitively impaired [SPMSQ (short portable mental status questionnaire ) m ± SD = 1.47 ± 0.794]. At 3-month follow-up patients with strength reduction had a relative risk of death more than seven times higher than the others (p = 0.047). Same results were observed at 1-year follow-up (95 % CI = 1.85-9.84; p = 0.000). There was no significant relationship between HGS and hospital re-admissions.
Effects of strength reduction occurring during a period of hospitalization could produce effects even after hospitalization itself. This increases the relevance of maintaining usual physical performance of patients even during hospitalization.
衰弱是一种常见的情况，常影响临床结局、残疾或住院。本研究旨在评估握力（HGS）降低对 3 个月和 1 年随访时死亡或再住院的影响。
对 65 岁及以上住院患者进行观察性研究。两次测量 HGS：入院时和出院时。使用 SPSS 18 for Windows 进行统计分析。χ 2 检验用于评估 HGS 与不同变量之间的关系。使用 Kaplan-Meier 曲线分析 3 个月和 1 年的生存率和再住院率。分析调整了年龄和性别。
共纳入 201 名住院患者，其中 76 名男性，平均年龄 81.79 ± 7.409 岁。所有纳入的患者中，66.2%和 45.3%分别没有任何日常生活活动和工具性日常生活活动的障碍。此外，患者的认知功能没有受损[SPMSQ（简短便携式精神状态问卷）m ± SD = 1.47 ± 0.794]。在 3 个月随访时，力量下降的患者死亡的相对风险是其他患者的 7 倍以上（p = 0.047）。在 1 年随访时也观察到了相同的结果（95%CI=1.85-9.84；p=0.000）。HGS 与再住院之间无显著关系。
住院期间发生的力量下降可能会在住院后产生影响。这增加了维持患者日常体能的相关性，即使在住院期间也是如此。
