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[电视辅助胸腔镜肺叶切除术——I期非小细胞肺癌治疗的标准术式?]

[VATS lobectomy--a standard procedure in the therapy for stage I non-small cell lung cancer?].

作者信息

Grallert M, Uhlmann D, Bartels M, Steinert M

机构信息

Klinik für Thoraxchirurgie, Martha-Maria Krankenhaus Halle-Dölau Deutschland.

出版信息

Zentralbl Chir. 2013 Oct;138 Suppl 1:S40-4. doi: 10.1055/s-0033-1350854. Epub 2013 Oct 22.

Abstract

Even though VATS lobectomy has been practised since 1991 in stage I of non-small cell lung cancer (NSCLC), it was not being considered equivalent to conventional lobectomy due to considerable doubts in terms of safety and oncological permissibility. This study describes our experience and an evaluation of the systematic establishment of lobectomy by means of video-assisted thoracic surgery (VATS) as standard treatment of NSCLC in stage I, which serves as an alternative to conventional surgery. For this purpose, 42 NSCLC patients in stage I, undergoing a conventional lobectomy in 2010 (group I), were retrospectively compared to 30 patients in the same tumour stage (group II) who were treated in 2011 using VATS lobectomy. The comparison of these two groups was drawn regarding operation time, number of resected lymph nodes, required analgesics, duration of drainage, rate of postoperative complications and length of hospital stay. Although VATS lobectomy requires a longer operation time of approximately 30 minutes, it shows significant advantages in reference to postoperative need of analgesics, duration of drainage and complications after surgery. Furthermore, the amount of resected lymph nodes was comparable in both groups. Therefore, VATS lobectomy constitutes an essential extension for the operative management in a lung cancer centre. Our results show that this new method is not only of equal, but of superior value compared to conventional lobectomy. Our experience and recent data in the literature illustrate that VATS lobectomy will play a decisive role in therapy for NSCLC in stage I, potentially even in stages II and IIIA.

摘要

尽管自1991年起就已开展非小细胞肺癌(NSCLC)I期的电视辅助胸腔镜肺叶切除术(VATS),但由于在安全性和肿瘤学可接受性方面存在诸多疑虑,它一直未被视为等同于传统肺叶切除术。本研究描述了我们的经验,并对通过电视辅助胸腔镜手术(VATS)系统开展肺叶切除术作为NSCLC I期的标准治疗方法进行了评估,该方法可作为传统手术的替代方案。为此,对2010年接受传统肺叶切除术的42例I期NSCLC患者(I组)与2011年接受VATS肺叶切除术的30例同一肿瘤分期患者(II组)进行了回顾性比较。比较了两组在手术时间、切除淋巴结数量、所需镇痛药、引流持续时间、术后并发症发生率和住院时间等方面的情况。尽管VATS肺叶切除术的手术时间大约要长30分钟,但在术后镇痛药需求、引流持续时间和术后并发症方面显示出显著优势。此外,两组切除的淋巴结数量相当。因此,VATS肺叶切除术是肺癌中心手术治疗的重要扩展。我们的结果表明,这种新方法不仅与传统肺叶切除术具有同等价值,而且具有更高的价值。我们的经验和近期文献数据表明,VATS肺叶切除术将在NSCLC I期治疗中发挥决定性作用,甚至在II期和IIIA期可能也如此。

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