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正电子发射断层扫描/计算机断层扫描在前列腺原发性非霍奇金淋巴瘤评估中的应用。

Positron emission tomography/computerized tomography in the evaluation of primary non-Hodgkin's lymphoma of prostate.

机构信息

Bo Pan, Jian-Kui Han, PET/CT Center, Qilu Hospital, the First Affiliated Hospital of Shandong University, Jinan 250012, Shandong Province, China.

出版信息

World J Gastroenterol. 2013 Oct 21;19(39):6699-702. doi: 10.3748/wjg.v19.i39.6699.

DOI:10.3748/wjg.v19.i39.6699
PMID:24151402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3801389/
Abstract

Primary malignant lymphoma of the prostate is exceedingly rare. Here we report a case of a 65-year-old man who presented with increased urinary frequency, urinary urgency, and urinary incontinence for two years. Benign prostatic hypertrophy was suspected at primary impression. Ultrasound revealed a hypoechoic lesion of the prostate. The total serum prostate-specific antigen was within normal range. Positron emission tomography/computerized tomography (PET/CT) showed a hypermetabolic prostatic lesion. Prostate biopsy was consistent with a non-germinal center diffuse large B cell lymphoma. There was complete remission of the prostatic lesion following six cycles of chemotherapy as shown on the second PET/CT imaging. ¹⁸F-fluoro-deoxy glucose PET/CT is not only a complement to conventional imaging, but also plays a significant role in the diagnosis and evaluation of treatment response of prostatic lymphoma.

摘要

前列腺原发性恶性淋巴瘤极为罕见。我们在此报告 1 例 65 岁男性患者,其主要表现为尿频、尿急和尿失禁 2 年。初步印象为良性前列腺增生。超声显示前列腺低回声病变。总前列腺特异性抗原在正常范围内。正电子发射断层扫描/计算机断层扫描(PET/CT)显示前列腺高代谢病变。前列腺活检与非生发中心弥漫性大 B 细胞淋巴瘤一致。在第二次 PET/CT 成像上,六周期化疗后前列腺病变完全缓解。¹⁸F-氟脱氧葡萄糖 PET/CT 不仅是常规成像的补充,而且在前列腺淋巴瘤的诊断和治疗反应评估中也具有重要作用。

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本文引用的文献

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FDG PET/CT imaging suggests lymphoma involving prostate may be more resistant to treatment.FDG PET/CT 成像表明,前列腺受累的淋巴瘤可能对治疗更具抵抗力。
Clin Nucl Med. 2011 Mar;36(3):255-7. doi: 10.1097/RLU.0b013e3181f9e012.
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FDG-PET/CT in evaluation and prognostication of primary prostate lymphoma.
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F-18 FDG PET/CT evaluation of radiotherapy response in rare case of mucosa-associated lymphoid tissue lymphoma.F-18 FDG PET/CT 评价罕见黏膜相关淋巴组织淋巴瘤放疗反应
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[Prostatic lymphoma and review of the literature].[前列腺淋巴瘤及文献综述]
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