Chen Tao-Fen, Lin Wen-Li, Liu Wen-Ya, Gu Chi-Ming
Department of Urology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510000, Guangdong Province, China.
World J Clin Cases. 2023 Mar 6;11(7):1627-1633. doi: 10.12998/wjcc.v11.i7.1627.
Prostate lymphoma has no characteristic clinical symptomatology, is often misdiagnosed, and currently, clinical case reports of this disease are relatively rare. The disease develops rapidly and is not sensitive to conventional treatment. A delay in the treatment of hydronephrosis may lead to renal function injury, often causing physical discomfort and rapid deterioration with the disease. This paper presents two patients with lymphoma of prostate origin, followed by a summary of the literature concerning the identification and treatment of such patients.
This paper reports on the cases of two patients with prostate lymphoma admitted to the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, one of whom died of the disease 2 mo after diagnosis, while the other was treated promptly, and his tumor was significantly reduced at the 6-mo follow-up.
The literature shows that prostate lymphoma is often seen as a benign prostate disease during its pathogenesis, even though primary prostate lymphoma enlarges rapidly and diffusely with the invasion of surrounding tissues and organs. In addition, prostate-specific antigen levels are not elevated and are not specific. There are no significant features in single imaging either, but during dynamic observation of imaging, it can be found that the lymphoma is diffusely enlarged locally and that systemic symptoms metastasize rapidly. The two cases of rare prostate lymphoma reported herein provide a reference for clinical decision making, and the authors conclude that early nephrostomy to relieve the obstruction plus chemotherapy is the most convenient and effective treatment option for the patient.
前列腺淋巴瘤没有特征性的临床症状，常被误诊，目前关于该疾病的临床病例报道相对较少。该疾病发展迅速，对传统治疗不敏感。肾积水治疗延迟可能导致肾功能损害，常引起身体不适且病情迅速恶化。本文介绍了两名前列腺原发淋巴瘤患者，并对这类患者的诊断与治疗的相关文献进行了总结。
本文报道了广州中医药大学第二附属医院收治的两名前列腺淋巴瘤患者的病例，其中一名患者在诊断后2个月死于该疾病，而另一名患者得到及时治疗，在6个月随访时肿瘤明显缩小。
文献表明，前列腺淋巴瘤在发病过程中常被视为良性前列腺疾病，尽管原发性前列腺淋巴瘤会迅速弥漫性增大并侵犯周围组织和器官。此外，前列腺特异性抗原水平不升高且不具有特异性。单一影像学检查也没有显著特征，但在影像学动态观察过程中，可以发现淋巴瘤局部弥漫性增大且全身症状转移迅速。本文报道的两例罕见前列腺淋巴瘤病例为临床决策提供了参考，作者认为早期肾造瘘解除梗阻加化疗是该患者最便捷有效的治疗选择。
