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醛固酮对未成熟雄性大鼠肾脏中胸苷激酶合成的诱导作用。

Induction of the synthesis of thymidine kinase by aldosterone in the kidney of the immature male rat.

作者信息

Bukhari A R, Hartmann H G, Jouan P

出版信息

Experientia. 1985 Nov 15;41(11):1449-51. doi: 10.1007/BF01950029.

DOI:10.1007/BF01950029
PMID:2415387
Abstract

Thymidine kinase activity was studied in kidneys from immature male rats after administration of aldosterone. Kinetic studies showed that the enzyme activity reached its maximum level 24 h after aldosterone injection. That increase was specific for aldosterone and could be related to the synthesis of new molecules of enzyme.

摘要

在给未成熟雄性大鼠注射醛固酮后，对其肾脏中的胸苷激酶活性进行了研究。动力学研究表明，醛固酮注射后24小时，该酶活性达到最高水平。这种增加是醛固酮所特有的，可能与新的酶分子合成有关。

相似文献

1
Induction of the synthesis of thymidine kinase by aldosterone in the kidney of the immature male rat.醛固酮对未成熟雄性大鼠肾脏中胸苷激酶合成的诱导作用。
Experientia. 1985 Nov 15;41(11):1449-51. doi: 10.1007/BF01950029.
2
Estrogen-like effect of 5-androstene-3 beta,17 beta-diol on the induction of fetal thymidine kinase in the rat uterus.5-雄烯-3β,17β-二醇对大鼠子宫中胎儿胸腺嘧啶激酶诱导的雌激素样作用。
J Steroid Biochem. 1988 Oct;31(4A):453-8. doi: 10.1016/0022-4731(88)90315-9.
3
Induction of flavokinase (EC 2.7.1.26) by aldosterone in the rat kidney.醛固酮对大鼠肾脏中黄素激酶（EC 2.7.1.26）的诱导作用。
Endocrinology. 1985 Mar;116(3):879-88. doi: 10.1210/endo-116-3-879.
4
Induction of rat pituitary thymidine kinase: another physiological response to oestradiol in the male?大鼠垂体胸苷激酶的诱导：雄性动物对雌二醇的另一种生理反应？
Mol Cell Endocrinol. 1975 Aug;3(2):117-27. doi: 10.1016/0303-7207(75)90058-1.
5
[Induction of thymidine kinase synthesis by 5-androstene-3 beta,17 beta-diol in the uterus of the immature rat].[5-雄烯-3β,17β-二醇对未成熟大鼠子宫中胸苷激酶合成的诱导作用]
C R Seances Soc Biol Fil. 1984;178(4):348-54.
6
[Induction, by 17 beta-estradiol, of thymidine kinase activity in uteri of rats].[17β-雌二醇对大鼠子宫中胸苷激酶活性的诱导作用]
C R Seances Soc Biol Fil. 1983;177(3):283-9.
7
Nongenomic effect of aldosterone on Na+,K+-adenosine triphosphatase in arterial vessels.醛固酮对动脉血管中钠钾-三磷酸腺苷酶的非基因组效应。
Endocrinology. 2003 Apr;144(4):1266-72. doi: 10.1210/en.2002-220950.
8
Effects of aldosterone, actinomycin D, puromycin and cycloheximide on RNA synthesis, carbonic anhydrase and ATPase activities of the kidney and on urinary excretion of sodium in adrenalectomized mice.醛固酮、放线菌素D、嘌呤霉素和环己酰亚胺对肾上腺切除小鼠肾脏RNA合成、碳酸酐酶和ATP酶活性以及尿钠排泄的影响。
J Steroid Biochem. 1976 Jun-Jul;7(6-7):429-38. doi: 10.1016/0022-4731(76)90108-4.
9
[Induction of fetal thymidine kinase by phyto-estrogens in the immature rat uterus].
C R Seances Soc Biol Fil. 1987;181(2):122-7.
10
Hormonal effects on Na-K-ATPase of various parts of the rat nephron.
Curr Probl Clin Biochem. 1975;4:214-7.

本文引用的文献

1
Binding of aldosterone to cytoplasmic and nuclear receptors of the rabbit kidney.醛固酮与兔肾细胞质及细胞核受体的结合
Am J Physiol. 1981 Jan;240(1):C20-7. doi: 10.1152/ajpcell.1981.240.1.C20.
2
Effect of chronic castration on testosterone and estrogen binding to mouse kidney.慢性去势对睾酮和雌激素与小鼠肾脏结合的影响。
J Steroid Biochem. 1980 Jul;13(7):781-6. doi: 10.1016/0022-4731(80)90229-0.
3
Stimulation by estradiol-17 beta of thymidine kinase activity in the rat uterus.17β-雌二醇对大鼠子宫中胸苷激酶活性的刺激作用。
J Steroid Biochem. 1984 Nov;21(5):613-20. doi: 10.1016/0022-4731(84)90339-x.
4
Aldosterone binding in isolated tubules II. An autoradiographic study of concentration dependency in the rabbit nephron.醛固酮在离体肾小管中的结合II. 兔肾单位浓度依赖性的放射自显影研究
Am J Physiol. 1982 Jan;242(1):F69-77. doi: 10.1152/ajprenal.1982.242.1.F69.
5
Autoradiographic study of nuclear localization of aldosterone binding sites in intact renal cells: lack of temperature dependency.完整肾细胞中醛固酮结合位点核定位的放射自显影研究：缺乏温度依赖性。
J Steroid Biochem. 1984 Feb;20(2):585-93. doi: 10.1016/0022-4731(84)90128-6.
6
Autoradiographic study of thermo-dependent nucleo-cytoplasmic distribution of aldosterone binding sites in intact target cells.
J Steroid Biochem. 1984 Jan;20(1):325-8. doi: 10.1016/0022-4731(84)90226-7.
7
[Induction, by 17 beta-estradiol, of thymidine kinase activity in uteri of rats].[17β-雌二醇对大鼠子宫中胸苷激酶活性的诱导作用]
C R Seances Soc Biol Fil. 1983;177(3):283-9.
8
Relationships between renal cytoplasmic and nuclear aldosterone-receptors.肾细胞质与核醛固酮受体之间的关系。
Kidney Int. 1972 Apr;1(4):210-23. doi: 10.1038/ki.1972.31.
9
An estrogen binding protein in the renal cytosol of intact, castrated and estrogenized golden hamsters.完整、阉割及雌激素处理的金黄仓鼠肾细胞溶质中的一种雌激素结合蛋白。
Endocrinology. 1974 Oct;95(4):1134-41. doi: 10.1210/endo-95-4-1134.
10
Renal aldosterone receptors: studies with (3H)aldosterone and the anti-mineralocorticoid (3H)spirolactone (SC-26304).肾醛固酮受体：用（3H）醛固酮和抗盐皮质激素（3H）螺内酯（SC - 26304）进行的研究
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1431-5. doi: 10.1073/pnas.71.4.1431.