Tan Lixian Chris, Tan Kong Bing, Aw Chen Wee Derrick
Singapore Med J. 2014 Feb;55(2):e25-7. doi: 10.11622/smedj.2013207.
Xanthogranulomas are the most common form of non-Langerhans cell histiocytosis. Both adult and childhood forms have been described. Adult cutaneous forms can present as solitary or multiple yellowish, orange-red or tan-hued papules. Herein, we present the case of a 28-year-old Chinese man with a skin-coloured nodule on his left nasal ala that persisted for several months. While initial impression was that of a fibrous papule of the nose, the results of an excision biopsy showed histological features corresponding to xanthogranuloma. This case demonstrates the condition’s myriad of dermatological presentations, and adds to the differential diagnoses of a cutaneous lesion found in the head and neck region.
黄色肉芽肿是非朗格汉斯细胞组织细胞增生症最常见的形式。成人和儿童形式均有描述。成人皮肤型可表现为单个或多个淡黄色、橙红色或棕褐色丘疹。在此,我们报告一例28岁中国男性,其左鼻翼有一个肤色结节,持续数月。最初诊断为鼻部纤维丘疹,但切除活检结果显示组织学特征符合黄色肉芽肿。该病例展示了该病众多的皮肤表现,并增加了头颈部皮肤病变的鉴别诊断。