Kirilmaz B, Asgun F, Saygi S, Ercan E
Department of Cardiology, Canakkale Onsekiz Mart University, 17100, Kepez, Canakkale, Turkey,
Herz. 2015 Feb;40(1):123-8. doi: 10.1007/s00059-013-3970-4. Epub 2013 Oct 25.
Left ventricular (LV) torsion is a sensitive indicator of myocardial contractility and cardiac structure, and has recently been recognized as a sensitive indicator of cardiac performance. The aim of our study was to assess the effect of isolated mitral stenosis on LV torsion.
We enrolled 19 patients with isolated mitral stenosis and 19 age- and gender-matched healthy subjects in the study. All patients had a normal sinus rhythm. All study subjects underwent two-dimensional echocardiography. Basal and apical LV rotations and LV torsion were evaluated using speckle-tracking echocardiography.
Demographic characteristics, basic echocardiographic measures of LV ejection fraction, LV wall thickness, and LV mass index were similar between the two groups. The degrees of LV torsion (11.3 ± 4.7, 15.4 ± 4.9°, p=0.014) and LV basal rotation (- 3.7 ± 1.9, - 6.5 ± 2.1°, p< 0.001) were significantly decreased in the mitral stenosis group. There was a moderate positive correlation between mitral valve area and LV torsion (r=0.531, p=0.019).
We showed significant reductions in LV torsion and LV basal rotation in patients with mitral valve stenosis. Structural and anatomical changes occurring during the progression of mitral stenosis may be responsible for these impaired movements.
左心室（LV）扭转是心肌收缩力和心脏结构的敏感指标，最近被认为是心脏功能的敏感指标。我们研究的目的是评估单纯二尖瓣狭窄对左心室扭转的影响。
我们招募了19例单纯二尖瓣狭窄患者和19例年龄及性别匹配的健康受试者进行研究。所有患者均为正常窦性心律。所有研究对象均接受二维超声心动图检查。使用斑点追踪超声心动图评估左心室基底和心尖的旋转以及左心室扭转情况。
两组之间的人口统计学特征、左心室射血分数、左心室壁厚度和左心室质量指数的基本超声心动图测量结果相似。二尖瓣狭窄组的左心室扭转程度（11.3±4.７，15.4±4.9°，p=0.014）和左心室基底旋转程度（-3.7±1.9，-6.5±2.1°，p<０.001）显著降低。二尖瓣瓣口面积与左心室扭转之间存在中度正相关（r=0.531，p=0.019）。
我们发现二尖瓣狭窄患者的左心室扭转和左心室基底旋转显著降低。二尖瓣狭窄进展过程中发生的结构和解剖学变化可能是这些运动受损的原因。
