Kadofuku T, Sato T
J Chromatogr. 1985 Sep 13;343(1):51-8. doi: 10.1016/s0378-4347(00)84567-3.
The changes in cellular proteins in regenerating rat liver after partial hepatectomy were examined by high-resolution two-dimensional electrophoresis. The cellular proteins in regenerating rat livers were separated into two fractions (soluble and insoluble protein fractions) and the proteins in each fraction were analysed by means of two-dimensional electrophoresis. A rapid increase in three proteins and a rapid decrease in two proteins were detected after partial hepatectomy. The changes in these proteins were in parallel with the regeneration rate of liver, suggesting a close relationship with the proliferation of liver after partial hepatectomy.
采用高分辨率二维电泳法检测部分肝切除术后再生大鼠肝脏中细胞蛋白质的变化。将再生大鼠肝脏中的细胞蛋白质分为两部分（可溶性和不溶性蛋白质部分），并通过二维电泳分析每部分中的蛋白质。部分肝切除术后检测到三种蛋白质迅速增加，两种蛋白质迅速减少。这些蛋白质的变化与肝脏再生率平行，表明与部分肝切除术后肝脏的增殖密切相关。
