Roh Mr, Goo Bc, Jung Jy, Chung Hj, Chung Ky
Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, South Korea.
Laser Ther. 2011;20(3):175-80. doi: 10.5978/islsm.20.175.
A variety of treatment modalities have been used to reduce the size of en-larged pores. The 1064 nm Nd:YAG laser, in addition to its role in removal of tattoos and age-related dyschromia, depilation and skin rejuvenation, may also play a role in reducing the size of enlarged pores. The present split-face controlled study assessed and compared the efficacy between the quasi long-pulsed (micropulsed) and the Q-switched modes of the Nd:YAG laser in the treatment of enlarged pores.
Twenty subjects with enlarged pores were recruited for the micropulsed vs Q-switched study, all treated with the same 1064 nm Nd:YAG laser system. Ten subjects were treated with the 300 µs micropulsed mode and the other ten subjects were treated with the 5 ns Q-switched mode. All subjects were treated on the right half of the face, the left half serving as an untreated control. Five laser sessions were performed. The pore sizes were measured using an image analysis program and the sebum level was measured with a Sebumeter(®) before and after the treatments.
The pore size and sebum level significantly decreased with treatment on the treated side (right cheek and right half of nose) in both the micropulsed and Q-switched modes compared to the control side (p<0.05), but without any statistically significant difference between the modes.
The micropulsed and Q-switched Nd:YAG laser treatments reduced pore size and sebum levels with more or less equal efficacy and with no adverse side effects.
已采用多种治疗方式来减小毛孔粗大的尺寸。1064纳米钕钇铝石榴石激光,除了在去除纹身、与年龄相关的色素沉着异常、脱毛及皮肤年轻化方面发挥作用外,在减小毛孔粗大尺寸方面可能也有作用。本半脸对照研究评估并比较了钕钇铝石榴石激光的准长脉冲(微脉冲)模式与调Q模式在治疗毛孔粗大方面的疗效。
招募了20名毛孔粗大的受试者参与微脉冲与调Q模式的研究,均采用同一台1064纳米钕钇铝石榴石激光系统进行治疗。10名受试者接受300微秒微脉冲模式治疗,另外10名受试者接受5纳秒调Q模式治疗。所有受试者均在右半脸进行治疗,左半脸作为未治疗对照。进行了5次激光治疗。在治疗前后,使用图像分析程序测量毛孔大小,并用皮脂仪测量皮脂水平。
与对照侧相比,微脉冲模式和调Q模式在治疗侧(右脸颊和右半侧鼻子)治疗后毛孔大小和皮脂水平均显著降低(p<0.05),但两种模式之间无任何统计学显著差异。
微脉冲和调Q钕钇铝石榴石激光治疗在减小毛孔大小和皮脂水平方面疗效大致相同,且无不良副作用。