Weissberg P L, West M J, Kendall M J, Ingram M, Woods K L
J Hypertens. 1985 Oct;3(5):475-80.
In a study on 22 normotensive male subjects, a change in dietary sodium intake from 29.6 +/- 6.0 to 332.5 +/- 13.9 mmol/day (mean +/- s.e.m.), over 7 days, was associated with a significant rise in supine and standing systolic blood pressure and a fall in sodium pump activity. Intracellular sodium remained constant, while intracellular potassium fell. These changes appeared to be reversed by the addition of potassium (96 mmol/day) to the high sodium diet. The 12 subjects with a family history of essential hypertension, as determined by measurement of parental blood pressure, did not differ in their response from those whose parents were normotensive.
在一项针对22名血压正常男性受试者的研究中，7天内饮食中钠摄入量从29.6±6.0毫摩尔/天增加到332.5±13.9毫摩尔/天（平均值±标准误），与仰卧位和站立位收缩压显著升高以及钠泵活性下降有关。细胞内钠含量保持不变，而细胞内钾含量下降。在高钠饮食中添加钾（96毫摩尔/天）后，这些变化似乎得到了逆转。通过测量父母血压确定有原发性高血压家族史的12名受试者，其反应与父母血压正常的受试者没有差异。
