Division of Interventional Neuroradiology, Departments of Neurosurgery and Radiology, University of Michigan Hospitals, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5030, USA.
Neuroimaging Clin N Am. 2013 Nov;23(4):593-604. doi: 10.1016/j.nic.2013.03.008. Epub 2013 May 24.
Cerebral vasospasm following aneurysmal subarachnoid hemorrhage (SAH) is a delayed, reversible narrowing of the intracranial vasculature that occurs most commonly 4 to 14 days after aneurysmal SAH and can lead to permanent ischemic injury. Angiographic spasm occurs in up to 70% of patients following SAH, and approximately half become symptomatic. Estimates of patients who are disabled by vasospasm, or die because of it, range from 5% to 9%, with vasospasm accounting for 12% to 17% of all fatalities or cases of disability after SAH. This article discusses the multiple medical and endovascular therapies used to prevent or treat vasospasm.
颅内血管痉挛是蛛网膜下腔出血（SAH）后的一种迟发性、可逆转的颅内血管狭窄，最常见于动脉瘤性 SAH 后 4 至 14 天发生，可导致永久性缺血性损伤。SAH 后高达 70%的患者出现血管痉挛，约一半出现症状。因血管痉挛而致残或死亡的患者估计为 5%至 9%，血管痉挛占 SAH 后所有死亡或致残病例的 12%至 17%。本文讨论了多种用于预防或治疗血管痉挛的药物和血管内治疗方法。
