Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Sleep Med. 2013 Dec;14(12):1356-63. doi: 10.1016/j.sleep.2013.09.004. Epub 2013 Oct 1.
We aimed to examine the association between various sleep disturbances and falls among older individuals from the general population while considering the influence of age and dizziness.
Data were derived from the population-based cross-sectional KORA (Cooperative Health Research in the Region of Augsburg)-Age study, whereby information was conducted in standardized telephone interviews with 4127 men and women aged ⩾65years in 2008 and 2009. Unstratified and stratified (by age and dizziness) multivariable logistic regression model analyses were performed.
The multivariable analysis showed a marginally significant association between trouble staying asleep and ⩾1 fall in the previous year (odds ratio [OR], 1.23 [95% confidence interval (CI), 1.01-1.50]). This association was more pronounced in participants older than the age of 75years (OR, 1.58 [95% CI, 1.16-2.16]) and in individuals without dizziness (OR, 1.35 [95% CI, 1.04-1.76]). There was no association between daytime sleepiness and falls in the fully-adjusted models, but the odds of falls in the previous year in individuals older than the age of 75years were significantly higher for individuals with difficulty falling asleep. Although sleep duration was not associated with falls in multivariable analyses when stratified by dizziness, sleep duration of 9h daily was significantly associated with higher odds of experiencing at least one fall in the previous year.
Our study suggested that the positive relationship between a trend towards longer sleep duration, trouble falling and staying asleep, and falls is strongest in older individuals and in individuals who did not experience dizziness in the previous year.
本研究旨在探讨一般人群中老年个体的各种睡眠障碍与跌倒之间的关系,同时考虑年龄和头晕的影响。
数据来自基于人群的横断面 KORA(奥格斯堡地区合作健康研究)-年龄研究,该研究于 2008 年和 2009 年通过标准化电话访谈对 ⩾65 岁的 4127 名男性和女性进行了调查。进行了未分层和分层(按年龄和头晕分层)多变量逻辑回归模型分析。
多变量分析显示,入睡困难与前一年 ⩾1 次跌倒之间存在边缘显著关联(比值比 [OR],1.23 [95%置信区间 (CI),1.01-1.50])。这种关联在年龄大于 75 岁的参与者中更为明显(OR,1.58 [95% CI,1.16-2.16]),在没有头晕的个体中更为明显(OR,1.35 [95% CI,1.04-1.76])。在完全调整的模型中,白天嗜睡与跌倒之间没有关联,但在年龄大于 75 岁的个体中,入睡困难者前一年跌倒的几率明显更高。尽管在按头晕分层的多变量分析中睡眠时间与跌倒无关,但每天睡眠 9 小时与前一年至少跌倒一次的几率显著相关。
我们的研究表明,睡眠持续时间较长、入睡和保持睡眠困难与跌倒之间的正相关关系在年龄较大的个体和前一年没有头晕的个体中最强。