鉴定法国男男性行为者中新型循环 B/CRF02/G 重组形式 CRF56_cpx。
Characterization of CRF56_cpx, a new circulating B/CRF02/G recombinant form identified in MSM in France.
机构信息
aLaboratoire associé au CNR du VIH, hôpital Ch. Nicolle, CHU de Rouen bGRAM EA 2656, Faculté de Médecine-Pharmacie, Université de Rouen, Rouen, France cComputational and Evolutionary Biology research group, Faculty of Life Science, University of Manchester, Manchester, UK dAssistance Publique - Hopitaux de Paris, Groupe Hospitalier Bichat Claude Bernard, Service de Virologie eAssistance Publique - Hopitaux de Paris, Groupe Hospitalier Saint Louis, Service de Virologie, fAssistance Publique - Hopitaux de Paris, Groupe Hospitalier Pitié Salpêtrière, Service de Virologie, Paris, France.
出版信息
AIDS. 2013 Sep 10;27(14):2309-12. doi: 10.1097/QAD.0b013e3283632e0c.
Several B/CRF02_AG Unique Recombinant Forms (URFs) have previously been identified in France. Here we show that one of them (URF5_B/02/G) is emerging in MSM, a high-risk population where HIV incidence and number of superinfections are increasing. We describe this new Circulating Recombinant Form, CRF56_cpx, estimate the time to its most recent common ancestor, investigate its origins and show that it probably shares common ancestors with strains from the East Mediterranean.
此前在法国已发现几种 B/CRF02_AG 独特重组形式 (URF)。在此，我们表明其中一种 (URF5_B/02/G) 正在男男性行为者（MSM）中出现，而 MSM 是 HIV 发病率和再感染人数不断增加的高危人群。我们描述了这种新的循环重组形式 CRF56_cpx，估计了其最近共同祖先的时间，研究了其起源，并表明它可能与来自东地中海的毒株有共同的祖先。
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