Budroni Mario, Sechi Ornelia, Cossu Antonio, Palmieri Giuseppe, Tanda Francesco, Foschi Roberto, Rossi Silvia
Tumori. 2013 May-Jun;99(3):408-15. doi: 10.1177/030089161309900317.
Cancer registration in Sardinia covers 43% of the population and started in 1992 in the Sassari province. The aim of this paper is to provide estimates of the incidence, mortality and prevalence of seven major cancers for the entire region in the period 1970-2015.
The estimates were obtained by applying the MIAMOD method, a statistical back-calculation approach to derive incidence and prevalence figures starting from mortality and relative survival data. Estimates were compared with the available observed data.
In 2012 the lowest incidence was estimated for stomach cancer and melanoma among men, with 140 and 74 new cases, respectively, per 100,000. The mortality rates were highest for lung cancer and were very close to the incidence rates (77 and 95 per 100,000, respectively). In women, breast was by far the most frequent cancer site both in terms of incidence (1,512 new cases) and mortality (295 deaths), followed by colon-rectum (493 cases and 201 deaths), lung (205 cases and 167 deaths), melanoma (106 cases and 15 deaths), stomach (82 cases and 61 deaths), and uterine cervix (36 cases and 19 deaths). The highest prevalence was estimated for breast cancer (15,180 cases), followed by colorectal cancer with about 7,300 prevalent cases in both sexes.
This paper provides a description of the burden of the major cancers in Sardinia until 2015. The comparisons between the estimated age-standardized incidence rates and those observed in the Sassari registry indicate good agreement. The estimates show a general decrease in cancer mortality, with the exception of female lung cancer. By contrast, the prevalence is steeply increasing for all considered cancers (with the only exception of cancer of the uterine cervix). This points to the need for more strongly supporting evidence-based prevention campaigns focused on contrasting female smoking, unhealthy nutrition and sun exposure.
撒丁岛的癌症登记覆盖了43%的人口，于1992年在萨萨里省启动。本文旨在提供1970 - 2015年期间该地区七种主要癌症的发病率、死亡率和患病率估计值。
通过应用MIAMOD方法获得估计值，这是一种从死亡率和相对生存数据推导发病率和患病率数据的统计反向计算方法。将估计值与现有的观察数据进行比较。
2012年，男性中胃癌和黑色素瘤的估计发病率最低，每10万人中分别有140例和74例新发病例。肺癌的死亡率最高，且非常接近发病率（分别为每10万人77例和95例）。在女性中，乳腺癌无论是发病率（1512例新发病例）还是死亡率（295例死亡）都是迄今为止最常见的癌症部位，其次是结肠直肠癌（493例病例和201例死亡）、肺癌（205例病例和167例死亡）、黑色素瘤（106例病例和15例死亡）、胃癌（82例病例和61例死亡）以及子宫颈癌（36例病例和19例死亡）。乳腺癌的估计患病率最高（15180例病例），其次是结肠直肠癌，两性合计约有7300例患病病例。
本文描述了截至2015年撒丁岛主要癌症的负担情况。估计的年龄标准化发病率与萨萨里登记处观察到的发病率之间的比较表明一致性良好。估计结果显示，除女性肺癌外，癌症死亡率总体呈下降趋势。相比之下，所有考虑的癌症患病率都在急剧上升（子宫颈癌除外）。这表明需要更有力地支持以证据为基础的预防运动，重点是减少女性吸烟、不健康饮食和日晒。
