Shishkina I V, Ozol' L Iu, Babichev V N
Ontogenez. 1985 Sep-Oct;16(5):506-12.
The content of estradiol receptors (E2) was studied in the cytoplasmic and nuclear fractions of the female rat hypothalamus and cortex during neonatal development. In the cytosol the E2-binding proteins, having a high capacity, include both true estradiol receptors and proteins identical with alpha-fetoprotein. True E2 receptors were found in the nuclear fraction: their concentration underwent almost no changes in hypothalamus and decreased from the 1st to the 5th day of postnatal development in cortex.
在新生大鼠发育过程中，对其下丘脑和皮质的胞质及核组分中的雌二醇受体（E2）含量进行了研究。在胞质溶胶中，具有高结合能力的E2结合蛋白包括真正的雌二醇受体和与甲胎蛋白相同的蛋白质。在核组分中发现了真正的E2受体：其在下丘脑中的浓度几乎没有变化，而在皮质中，从出生后第1天到第5天其浓度下降。
