Babichev V N, Peryshkova T A
Probl Endokrinol (Mosk). 1978 Nov-Dec;24(6):55-9.
Estradiol receptors content in the hypothalamus of female rats during the postnatal development (the 7th, 14th, 21st, 28th, 35th, and 42nd days) was studied. The greatest values of the binding capacity were revealed in the hypothalamus of 7- and 14-day female rats; thses values decreased gradually till sexual maturation. The number of estradiol receptors increased after the vagina opening in rats. Estradiol receptors possessed high sterospecificity and high degree of affinity to the receptive hormone.
研究了雌性大鼠出生后发育期间(第7、14、21、28、35和42天)下丘脑雌二醇受体含量。在7日龄和14日龄雌性大鼠的下丘脑中发现结合能力的最大值;这些值逐渐下降直至性成熟。大鼠阴道开口后雌二醇受体数量增加。雌二醇受体具有高度的立体特异性和对受体激素的高度亲和力。