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[大鼠雌性下丘脑胞质中雌二醇受体浓度在出生后发育过程中的变化动态]

[Dynamics of changes in the concentration of estradiol receptors in the cytosol of rat female hypothalamus during postnatal development].

作者信息

Babichev V N, Peryshkova T A

出版信息

Probl Endokrinol (Mosk). 1978 Nov-Dec;24(6):55-9.

PMID:724675
Abstract

Estradiol receptors content in the hypothalamus of female rats during the postnatal development (the 7th, 14th, 21st, 28th, 35th, and 42nd days) was studied. The greatest values of the binding capacity were revealed in the hypothalamus of 7- and 14-day female rats; thses values decreased gradually till sexual maturation. The number of estradiol receptors increased after the vagina opening in rats. Estradiol receptors possessed high sterospecificity and high degree of affinity to the receptive hormone.

摘要

研究了雌性大鼠出生后发育期间(第7、14、21、28、35和42天)下丘脑雌二醇受体含量。在7日龄和14日龄雌性大鼠的下丘脑中发现结合能力的最大值;这些值逐渐下降直至性成熟。大鼠阴道开口后雌二醇受体数量增加。雌二醇受体具有高度的立体特异性和对受体激素的高度亲和力。

相似文献

1
[Dynamics of changes in the concentration of estradiol receptors in the cytosol of rat female hypothalamus during postnatal development].[大鼠雌性下丘脑胞质中雌二醇受体浓度在出生后发育过程中的变化动态]
Probl Endokrinol (Mosk). 1978 Nov-Dec;24(6):55-9.
2
[Dynamics of the changes in the content of testosterone and estradiol receptors in the hypothalamus of male rats in the course of sexual development].
Ontogenez. 1983 Jan-Feb;14(1):57-63.
3
[Cytoplasmic and nuclear receptors of estradiol in the hypothalamus and cerebral cortex of female rats in the neonatal period].新生雌性大鼠下丘脑和大脑皮质中雌二醇的细胞质和核受体
Ontogenez. 1985 Sep-Oct;16(5):506-12.
4
[Sex hormone receptors in the hypothalamus and their role in the sexual differentiation of the brain of male rats].
Biull Eksp Biol Med. 1986 Apr;101(4):484-6.
5
[Dynamics of the content of estradiol cytoplasmic and nuclear receptors in the rat hypothalamus in the course of the estrous cycle and postnatal development].
Ontogenez. 1981;12(4):390-7.
6
[Hypothalamic receptors of sex hormones in the mechanism of the sexual differentiation of the brain in rats].
Zh Evol Biokhim Fiziol. 1987 Mar-Apr;23(2):216-23.
7
[Dynamics of changes in the estradiol receptor content in the nuclear fraction of the hypothalamus of female rats during ontogenesis].[雌性大鼠个体发育过程中下丘脑细胞核部分雌二醇受体含量的变化动态]
Probl Endokrinol (Mosk). 1980 Jul-Aug;26(4):55-60.
8
Androgen and estrogen receptors in the developing mouse brain.发育中小鼠大脑中的雄激素和雌激素受体。
Endocrinology. 1976 Nov;99(5):1279-90. doi: 10.1210/endo-99-5-1279.
9
A discontinuous schedule of estradiol treatment is sufficient to activate progesterone-facilitated feminine sexual behavior and to increase cytosol receptors for progestins in the hypothalamus of the rat.间断性雌二醇治疗足以激活孕酮促进的雌性性行为,并增加大鼠下丘脑孕激素的胞质受体。
Endocrinology. 1982 Feb;110(2):613-9. doi: 10.1210/endo-110-2-613.
10
[Estradiol receptors in the hypothalamus of androgenized female and castrated male rats].
Ontogenez. 1981;12(2):167-71.

引用本文的文献

1
Dynamics of the change in the content of estradiol receptors in the nuclear fraction of the hypothalamus of female rats during ontogenesis.
Neurosci Behav Physiol. 1981 Jul-Aug;11(4):396-9. doi: 10.1007/BF01184209.
2
Receptor binding of estradiol and testosterone in female rat pituitary.雌二醇和睾酮在雌性大鼠垂体中的受体结合
Neurosci Behav Physiol. 1987 Mar-Apr;17(2):172-5. doi: 10.1007/BF01184911.