Melrose M A, Magargal L E, Lucier A C
Ophthalmic Surg. 1985 Oct;16(10):648-51.
This is the first report, to our knowledge, of proliferative macular degeneration developing in the same eye of identical twins. The concept of a familial predisposition in age related macular degeneration is consistent with other known risk factors including race, iris pigmentation, hyperopia and macular drusen which are known to be genetically determined. Monozygotic twins provide ophthalmology with an excellent opportunity to study the hereditary aspects of ocular disease.
据我们所知，这是关于同卵双胞胎同一只眼睛发生增生性黄斑变性的首例报告。年龄相关性黄斑变性存在家族易感性这一概念，与其他已知的风险因素相符，这些因素包括种族、虹膜色素沉着、远视和黄斑玻璃疣，而这些因素已知是由基因决定的。同卵双胞胎为眼科研究眼部疾病的遗传因素提供了绝佳机会。
