Thomas G M, Rees P, Dippy J E, Maddock J
Curr Med Res Opin. 1975;3(5):264-7. doi: 10.1185/03007997509114776.
The simultaneous pharmacokinetics of alclofenac in the plasma and synovial fluid of 10 patients with rheumatoid arthritis were studied after a single 1 g. oral dose. A gas-liquid chromatographic method was used for assaying alclofenac in both plasma and synovial fluid. Alclofenac readily appears in the plasma and synovial fluid.