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Simultaneous pharmacokinetics of alclofenace in plasma and synovial fluid in patients with rheumatoid arthritis.

作者信息

Thomas G M, Rees P, Dippy J E, Maddock J

出版信息

Curr Med Res Opin. 1975;3(5):264-7. doi: 10.1185/03007997509114776.

Abstract

The simultaneous pharmacokinetics of alclofenac in the plasma and synovial fluid of 10 patients with rheumatoid arthritis were studied after a single 1 g. oral dose. A gas-liquid chromatographic method was used for assaying alclofenac in both plasma and synovial fluid. Alclofenac readily appears in the plasma and synovial fluid.

摘要

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