de Luis D A, Izaola O, Cuellar L, Terroba M C, Ventosa M, Martin T, Aller R
Center of Investigation of Endocrinology and Clinical Nutrition. Medicine School and Unit of Investigation Hospital Rio Hortega. University of Valladolid. Valladolid. Spain. Svo Endocrinología y Nutrición. Hospital Clínico Universitario de Valladolid. Valladolid. España.
Nutr Hosp. 2013 Sep-Oct;28(5):1463-7. doi: 10.3305/nh.2013.28.5.6662.
Patients with head and neck cancer undergoing surgery have a high risk of nutritional complications.
The aim of our study was to investigate the influence of an oral w3 enriched immunoenhanced powdered formula in nutritional and biochemical parameters in postsurgical ambulatory patients with head and neck tumor.
A population of 33 ambulatory postsurgical patients with oral and laryngeal cancer was enrolled. At Hospital discharge postsurgical head and neck cancer patients were asked to consume two units per day of a w3 enriched immunoenhanced powdered formula for a twelve week period.
The mean age was 61.3 ± 9.1 years (6 female/27 males). Duration of supplementation was 95.9 ± 21.1 days. A significant increase of albumin and transferrin levels was observed, in total group and in patients undergoing radiotherapy and without it. No differences were detected in weight and other anthropometric parameters in total group and in patients with radiotherapy during the protocol. Nevertheless, patients without radiotherapy showed a significant improvement of BMI; weight, fat free mass and fat mass.
At dose used, an omega 3 enriched powdered formula improved seric protein levels in ambulatory postoperative head and neck cancer patients. Improvement of weight, fat mass and fat free mass was observed in patients whom not received radiotherapy during the follow up.
接受手术的头颈癌患者发生营养并发症的风险很高。
我们研究的目的是调查口服富含w3的免疫增强型粉状配方对门诊头颈肿瘤术后患者营养和生化参数的影响。
招募了33名头颈癌术后门诊患者。头颈癌术后患者出院时被要求在12周内每天食用两单位富含w3的免疫增强型粉状配方。
平均年龄为61.3±9.1岁(6名女性/27名男性)。补充时间为95.9±21.1天。在整个组以及接受放疗和未接受放疗的患者中,白蛋白和转铁蛋白水平均显著升高。在整个组以及方案期间接受放疗的患者中,体重和其他人体测量参数未发现差异。然而,未接受放疗的患者的BMI、体重、去脂体重和脂肪量有显著改善。
在所使用的剂量下,富含ω-3的粉状配方改善了门诊头颈癌术后患者的血清蛋白水平。在随访期间未接受放疗的患者中观察到体重、脂肪量和去脂体重有所改善。