de Luis D A, de la Fuente B, Izaola O, Martin T, Cuellar L, Terroba M C
Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School and Dept Endocrinology and Nutrition, Hospital Clínico Universitario, University of Valladolid, Valladolid. Spain..
Nutr Hosp. 2014 Nov 30;31(2):759-63. doi: 10.3305/nh.2015.31.2.8481.
Patients with head and neck cancer undergoing surgery have a high risk of nutritional complications.
The aim of our study was to investigate the influence of a hypercaloric and hyperproteic oral supplement enriched with w3 FATTY ACIDS and fiber in clinical parameters in head and neck tumor postsurgical ambulatory patients with or without radiotherapy.
A population of 37 ambulatory postsurgical patients with oral and laryngeal cancer was enrolled. At Hospital discharge postsurgical head and neck cancer patients were asked to consume two units per day of a hypercaloric and hyperproteic oral supplement for a twelve week period.
The mean age was 63.8+/-7.1 years (16 female/ 21 males). Duration of supplementation was 98.1±19.1 days. A significant increase of albumin and transferrin levels was observed, in total group and in patients undergoing radiotherapy and without it. No differences were detected in weight and other anthropometric parameters in total group and in patients with radiotherapy during the protocol. Nevertheless, patients without radiotherapy showed a significant improvement of BMI; weight, fat free mass and fat mass.
An omega 3 and fiber enriched formula improved seric protein levels in ambulatory postoperative head and neck cancer patients. Improvement of weight, fat mass and fat free mass was observed in patients whom not received radiotherapy during the follow up.
接受手术的头颈癌患者发生营养并发症的风险很高。
我们研究的目的是调查富含w3脂肪酸和纤维的高热量、高蛋白口服补充剂对接受或未接受放疗的头颈肿瘤术后门诊患者临床参数的影响。
招募了37名口腔和喉癌术后门诊患者。头颈癌术后患者出院时被要求在12周内每天服用两单位高热量、高蛋白口服补充剂。
平均年龄为63.8±7.1岁(16名女性/21名男性)。补充时间为98.1±19.1天。在总组以及接受放疗和未接受放疗的患者中,观察到白蛋白和转铁蛋白水平显著升高。在方案期间,总组和接受放疗的患者在体重和其他人体测量参数方面未检测到差异。然而,未接受放疗的患者的BMI、体重、去脂体重和脂肪量有显著改善。
富含ω-3和纤维的配方改善了头颈癌术后门诊患者的血清蛋白水平。在随访期间未接受放疗的患者中观察到体重、脂肪量和去脂体重有所改善。