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接种疫苗后发生腮腺炎睾丸炎。

Case of mumps orchitis after vaccination.

机构信息

Department of Urology, Nihon University School of Medicine, Tokyo, Japan.

出版信息

Int J Urol. 2014 Apr;21(4):426-8. doi: 10.1111/iju.12305. Epub 2013 Oct 24.

Abstract

We present a case of mumps orchitis after vaccination. A 35-year-old man visited the emergency unit of our hospital for fever and right testicular pain on 7 January 2012. Two weeks before the visit, he underwent vaccination for mumps. After 7 days of hospitalization, the patient recovered from fever and testicular pain. Scrotal magnetic resonance imaging suggested right orchitis, and an increased level of serum mumps immunoglobulin M and immunoglobulin G indicated an initial infection of mumps virus. The peak value of immunoglobulin G showed 106 enzyme immunoassay unit 5 weeks after vaccination, which was 10-fold higher than the ordinary rise of a vaccinated individual. This fact leads to two possibilities. One is this happened as an adverse event of vaccination, and the other is that he actually had a wild-type infection at the same time as vaccination. There are some reports regarding adverse events of mumps vaccine; however, they might include wild-type infection.

摘要

我们报告了一例接种后腮腺炎睾丸炎病例。一名 35 岁男性于 2012 年 1 月 7 日因发热和右侧睾丸疼痛到我院急诊就诊。就诊前两周,他接受了腮腺炎疫苗接种。住院 7 天后,患者发热和睾丸疼痛消退。阴囊磁共振成像提示右侧睾丸炎,血清腮腺炎免疫球蛋白 M 和免疫球蛋白 G 水平升高提示腮腺炎病毒初次感染。接种后 5 周时,免疫球蛋白 G 的峰值达到 106 酶免疫分析单位,是接种个体普通升高的 10 倍。这一事实存在两种可能性。一种是这是接种的不良反应,另一种是他实际上在接种时同时发生了野毒株感染。有一些关于腮腺炎疫苗不良反应的报告,但它们可能包括野毒株感染。

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