Das I
Clin Chim Acta. 1985 Nov 29;153(1):9-13. doi: 10.1016/0009-8981(85)90133-0.
Investigation of a possible quantitative relationship between the extent of tissue injury due to inhalation of tobacco smoke and changes in concentrations of a number of acute phase proteins were studied in smokers. Smokers showed an acute phase response as indicated by significantly raised serum C-reactive protein levels. Significant lowering of serum albumin levels was also observed in smokers. Serum levels of alpha 1-antitrypsin, alpha 1-antichymotrypsin, alpha 1-acid glycoprotein, transferrin and haptoglobin did not show any significant changes due to inhalation of tobacco smoke. Although the C-reactive protein test is non-specific, evidence for elevated levels of C-reactive protein indicates the presence of tissue inflammation.
对吸烟者吸入烟草烟雾所致组织损伤程度与多种急性期蛋白浓度变化之间可能存在的定量关系进行了研究。吸烟者表现出急性期反应，血清C反应蛋白水平显著升高即表明了这一点。在吸烟者中还观察到血清白蛋白水平显著降低。吸入烟草烟雾后，α1-抗胰蛋白酶、α1-抗糜蛋白酶、α1-酸性糖蛋白、转铁蛋白和触珠蛋白的血清水平未显示出任何显著变化。尽管C反应蛋白检测是非特异性的，但C反应蛋白水平升高的证据表明存在组织炎症。
