Carlson J R, Hogness D S
Dev Biol. 1985 Apr;108(2):355-68. doi: 10.1016/0012-1606(85)90039-9.
The Jonah genes are expressed twice in development: Jonah RNA is detected during all larval stages, disappears at the end of the third larval instar, and then reappears shortly after eclosion, in the adult midgut. Construction and analysis of Jonah cDNA clones reveals that multiple Jonah genes are transcribed; cDNA clones deriving from at least four different clusters of Jonah genes have been identified. In at least one case, multiple genes in a cluster are transcribed, and one cluster is found to be transcribed both in larvae and adults. Evidence that different Jonah genes are under different control with respect to both spatial and temporal patterns of expression has been provided. Jonah RNA encodes a 28-kDa translation product or products for which we consider a possible function. Jonah RNA of constant length is found to be conserved in all strains of Drosophila melanogaster examined, Jonah genes are found at a minimum of three common chromosomal sites in all of seven D. melanogaster strains examined, and multiple Jonah genes are found in other Drosophila species.
在所有幼虫阶段都能检测到乔纳RNA，在第三龄幼虫末期消失，然后在羽化后不久在成虫中肠再次出现。乔纳cDNA克隆的构建和分析表明有多个乔纳基因被转录；已鉴定出至少来自四个不同乔纳基因簇的cDNA克隆。至少在一种情况下，一个基因簇中的多个基因被转录，并且发现一个基因簇在幼虫和成虫中都被转录。已经提供了证据表明不同的乔纳基因在表达的空间和时间模式方面受到不同的控制。乔纳RNA编码一种或多种28 kDa的翻译产物，我们认为其具有可能的功能。在所有检测的黑腹果蝇菌株中，发现长度恒定的乔纳RNA是保守的，在所有检测的七个黑腹果蝇菌株中，至少在三个常见染色体位点发现了乔纳基因，并且在其他果蝇物种中也发现了多个乔纳基因。
