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[重力白细胞分离术后粒细胞功能检测]

[Testing of granulocyte function after gravity leukapheresis].

作者信息

Steinhauer E U, Steinhauer A, Jorke D

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1985;112(5):669-82.

PMID:2416643
Abstract

In a laboratory model granulocyte concentrates are produced by a procedure of gravitational leukopheresis. Hydroxyaethyl starch (HAS) served as an accelerator of sedimentation. In a parallel test arrangement a preparation of hydroxyaethyl taken from the industrial production of the GDR and a control preparation (Plasmasteril) was used. The regaining rate of this method amounts to about 70 per cent with 98 per cent of living cells in the concentrates. Vitality, performance of phagocytosis and ability of migration will only reduce to a slight degree during the first 4 hours, after that time, however, they will decrease significantly. There are no essential differences between the results of both preparations.

摘要

在实验室模型中,通过重力白细胞分离术制备粒细胞浓缩物。羟乙基淀粉(HAS)用作沉降促进剂。在平行试验装置中,使用了从民主德国工业生产中获取的羟乙基制剂和一种对照制剂(血浆灭菌剂)。该方法的回收率约为70%,浓缩物中活细胞占98%。活力、吞噬性能和迁移能力在最初4小时内只会略有下降,但此后会显著降低。两种制剂的结果没有本质差异。

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