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小叶榕的生药学与植物化学研究

Pharmacognostic and phytochemical studies on Ficus Microcarpa L. fil.

作者信息

Kalaskar Mohan G, Surana Sanjay J

机构信息

Department of Pharmacognosy, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Dhule, Maharashtra, India.

出版信息

Anc Sci Life. 2012 Oct;32(2):107-11. doi: 10.4103/0257-7941.118550.

Abstract

BACKGROUND

Ficus microcarpa L. fil. (Syn: Ficus retusa) (Moraceae) is well-known traditional medicinal plant. The bark is used for diverse health ailments in traditional and folklore remedies.

AIMS

The present study was undertaken to lay down pharmacognostical and phytochemical standards.

MATERIALS AND METHODS

Pharmacognostic studies on fresh, dried and powdered bark was carried out to determine it's morphological, anatomical, and phytochemical diagnostic features. Furthermore, major phytoconstituents were identified from the extracts with the help of high performance liquid chromatography (HPLC) study.

RESULTS

The morphology showed to be soft, brittle, rough, shallow vertical, irregularly oriented fissures, curved surface; with splintering, laminated fracture. Microscopically F. microcarpa showed all general characteristics of bark with some distinct differentiation. The phellem is thin and even, phelloderm few cell and rectangular and followed by smaller sclerides, the phloem rays are broad, multi-serrate and showed the scattered bundles of sclerides. The fluorescence and physicochemical standards for bark were established. HPLC analysis showed the predominant presence of therapeutically important phytoconstituents such as oleanolic, betulinic acid, lupeol, β-sitosterol, catechin, and gallic acid.

CONCLUSION

The bark of F. microcarpa considered equivalent to other Ficus species, such as Ficus virens, Ficus infectoria, Ficus arnottiana, Ficus lacor, and Ficus talboti. However, there is no pharmacognostical and phytochemical reports on F. microcarpa to authenticate and differentiate it from similar species. Present work has described pharmacognostical and phytochemical characteristics of F. microcarpa and diagnostic features to differentiate it.

摘要

背景

小叶榕(同义词:榕树)(桑科)是一种著名的传统药用植物。在传统和民间疗法中,其树皮被用于治疗多种健康疾病。

目的

本研究旨在制定生药学和植物化学标准。

材料与方法

对新鲜、干燥和粉末状的树皮进行生药学研究,以确定其形态、解剖和植物化学诊断特征。此外,借助高效液相色谱(HPLC)研究从提取物中鉴定主要植物成分。

结果

形态上表现为柔软、易碎、粗糙、有浅垂直、不规则取向的裂缝、表面弯曲;有碎片状、层状断裂。在显微镜下,小叶榕显示出树皮的所有一般特征,并伴有一些明显的差异。木栓层薄且均匀,栓内层细胞少且呈长方形,其后是较小的石细胞,韧皮射线宽、多锯齿状,并显示出分散的石细胞束。建立了树皮的荧光和理化标准。HPLC分析表明,主要存在具有重要治疗作用的植物成分,如齐墩果酸、桦木酸、羽扇豆醇、β-谷甾醇、儿茶素和没食子酸。

结论

小叶榕的树皮被认为与其他榕属物种相当,如黄葛树、无花果、阿诺特榕、聚果榕和塔氏榕。然而,目前尚无关于小叶榕的生药学和植物化学报告来对其进行鉴定并与相似物种区分开来。本研究描述了小叶榕的生药学和植物化学特征以及用于区分它的诊断特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/176e/3807953/3400de2aa9cb/ASL-32-107-g001.jpg

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