The Institue of Cytology and Genetics, 90, Novosibirsk, Russia.
Theor Appl Genet. 1995 Nov;91(6-7):1095-100. doi: 10.1007/BF00223925.
We wanted to determine whether there is a correlation between the quantitative character, the penetrance of the loss of humeral bristles in scute lines, and the distribution of transposable genetic elements in their genomes. We derived 18 isogenic lines with penetrance ranging between 2.8% and 92.0% from six mutant lines. The localization of the transposable elements (TEs) P, mdg1, Dm412, copia, gypsy and B104 was determined in all isogenic derivatives by in situ hybridization. The total number of the TE sites over all lines was 180. A comparison of the distribution of the TEs in the isogenic lines revealed the location of sites typical of lines with similar penetrance, no matter which parental line was involved. The results obtained suggest that such typical sites appear to tag the genome regions where the polygenes affecting the character in question are most likely to be found.
我们想确定在数量特征、肱骨刚毛损失在盾线中的穿透率，以及它们基因组中转座遗传元件的分布之间是否存在相关性。我们从六个突变系中衍生出 18 条具有 2.8%至 92.0%穿透率的同基因系。通过原位杂交，确定了所有同基因衍生系中转座元件 (TE) P、mdg1、Dm412、copia、gypsy 和 B104 的位置。所有系的 TE 位点总数为 180 个。对同基因系中 TE 的分布进行比较，揭示了无论涉及哪个亲本系，具有相似穿透率的系中典型位点的位置。所得结果表明，这种典型的位点似乎标记了影响所研究特征的多基因最有可能存在的基因组区域。
