Lima Alexandre Moretti de, Sperandio Vitor Arantes, Rocha Sheila Pereira da, Ribeiro Beatriz Medeiros de, Reis Carmelia Matos Santiago
Federal University of Mato Grosso do Sul, Campo GrandeMS, Brazil.
An Bras Dermatol. 2013 Sep-Oct;88(5):836-8. doi: 10.1590/abd1806-4841.20132112.
The hyperimmunoglobulin E syndrome, or Job's syndrome is a rare primary immunodeficiency characterized by recurrent skin abscesses, recurrent respiratory tract infections, and high levels of IgE, eosinophilia, bone and dental changes. We report the case of a fourteen-year-old male patient presenting this disease, with both typical and also some relatively sporadic manifestations. We performed a literature review on the syndrome and its associated clinical findings.
高免疫球蛋白E综合征，即乔布综合征，是一种罕见的原发性免疫缺陷病，其特征为反复出现皮肤脓肿、反复发生呼吸道感染、高水平的免疫球蛋白E、嗜酸性粒细胞增多以及骨骼和牙齿改变。我们报告了一名患有该疾病的14岁男性患者的病例，该患者既有典型表现，也有一些相对散在的表现。我们对该综合征及其相关临床发现进行了文献综述。
