Eckfeldt J H, Kershaw M J
Arch Intern Med. 1986 Jan;146(1):193-4.
Methyl alcohol intoxication has been reported to cause hyperamylasemia and pancreatitis. We describe a patient with severe, nonfatal methyl alcohol intoxication who had a rise in serum amylase activity with the level peaked on the second hospital day at tenfold the upper limit of normal. However, isoamylase analysis showed that this striking hyperamylasemia was due to salivary-type amylase. Furthermore, the serum lipase activity remained entirely normal during the peak amylase elevation. Thus, in cases of methyl alcohol intoxication, as in other clinical situations, hyperamylasemia, even when striking, should not be equated with pancreatitis. More specific laboratory tests for pancreatitis should be used before embarking on extensive investigations of the pancreas.
据报道，甲醇中毒可导致高淀粉酶血症和胰腺炎。我们描述了一名患有严重非致命性甲醇中毒的患者，其血清淀粉酶活性升高，在住院第二天达到峰值，为正常上限的10倍。然而，同工酶分析显示，这种显著的高淀粉酶血症是由唾液型淀粉酶引起的。此外，在淀粉酶升高的峰值期间，血清脂肪酶活性完全正常。因此，在甲醇中毒的病例中，与其他临床情况一样，即使高淀粉酶血症很显著，也不应将其等同于胰腺炎。在对胰腺进行广泛检查之前，应使用更具特异性的胰腺炎实验室检查。
