Somers Julian M, Patterson Michelle L, Moniruzzaman Akm, Currie Lauren, Rezansoff Stefanie N, Palepu Anita, Fryer Karen
Somers Research Group, Faculty of Health Sciences Simon Fraser University, 8888 University Drive, Burnaby V5A 1S6, Canada.
Trials. 2013 Nov 1;14:365. doi: 10.1186/1745-6215-14-365.
Individuals with mental illnesses are overrepresented among the homeless. Housing First (HF) has been shown to promote positive outcomes in this population. However, key questions remain unresolved, including: how to match support services to client needs, the benefits of housing in scattered sites versus single congregate building, and the effectiveness of HF with individuals actively using substances. The present study aimed to recruit two samples of homeless mentally ill participants who differed in the complexity of their needs. Study details, including recruitment, randomization, and follow-up, are presented.
Eligibility was based on homeless status and current mental disorder. Participants were classified as either moderate needs (MN) or high needs (HN). Those with MN were randomized to HF with Intensive Case Management (HF-ICM) or usual care. Those with HN were randomized to HF with Assertive Community Treatment (HF-ACT), congregate housing with support, or usual care. Participants were interviewed every 3 months for 2 years. Separate consent was sought to access administrative data.
Participants met eligibility for either MN (n = 200) or HN (n = 297) and were randomized accordingly. Both samples were primarily male and white. Compared to participants designated MN, HN participants had higher rates of hospitalization for psychiatric reasons prior to randomization, were younger at the time of recruitment, younger when first homeless, more likely to meet criteria for substance dependence, and less likely to have completed high school. Across all study arms, between 92% and 100% of participants were followed over 24 months post-randomization. Minimal significant differences were found between study arms following randomization. 438 participants (88%) provided consent to access administrative data.
The study successfully recruited participants meeting criteria for homelessness and current mental disorder. Both MN and HN groups had high rates of substance dependence, suicidality, and physical illness. Randomization resulted in no meaningful detectable differences between study arms.
Current Controlled Trials: ISRCTN57595077 (Vancouver at Home study: Housing First plus Assertive Community Treatment versus congregate housing plus supports versus treatment as usual) and ISRCTN66721740 (Vancouver At Home study: Housing First plus Intensive Case Management versus treatment as usual).
在无家可归者中,患有精神疾病的人占比过高。“先提供住房”(HF)已被证明能在这一人群中促进积极的结果。然而,一些关键问题仍未得到解决,包括:如何使支持服务与客户需求相匹配、分散地点的住房与单一集合建筑住房的益处,以及“先提供住房”模式对积极使用毒品者的有效性。本研究旨在招募两组需求复杂程度不同的无家可归且患有精神疾病的参与者。文中介绍了研究细节,包括招募、随机分组和随访情况。
入选标准基于无家可归状态和当前的精神障碍。参与者被分为中度需求(MN)组或高度需求(HN)组。中度需求组被随机分配到接受强化个案管理的“先提供住房”模式(HF-ICM)或常规护理组。高度需求组被随机分配到接受积极社区治疗的“先提供住房”模式(HF-ACT)、有支持的集合住房组或常规护理组。参与者在两年内每3个月接受一次访谈。获取行政数据需另行征得同意。
参与者符合中度需求(n = 200)或高度需求(n = 297)的入选标准,并据此进行了随机分组。两组样本主要为男性和白人。与被指定为中度需求的参与者相比,高度需求组参与者在随机分组前因精神疾病住院的比例更高,招募时更年轻,首次无家可归时更年轻,更有可能符合药物依赖标准,且完成高中学业的可能性更小。在所有研究组中,随机分组后超过92%至100%的参与者在24个月内接受了随访。随机分组后各研究组之间未发现显著差异。438名参与者(88%)同意获取行政数据。
该研究成功招募了符合无家可归和当前精神障碍标准的参与者。中度需求组和高度需求组的药物依赖、自杀倾向和身体疾病发生率都很高。随机分组后各研究组之间未发现有意义的可检测差异。
当前受控试验:ISRCTN57595077(温哥华居家研究:“先提供住房”加积极社区治疗与集合住房加支持与常规治疗对比)和ISRCTN66721740(温哥华居家研究:“先提供住房”加强化个案管理与常规治疗对比)。