Department of Psychiatry, Stanford University, Stanford, CA, United States.
Eat Behav. 2013 Dec;14(4):488-92. doi: 10.1016/j.eatbeh.2013.08.002. Epub 2013 Aug 15.
Self-report studies suggest that patients with bulimia nervosa (BN) evidence difficulties with interoceptive awareness. Indeed, interoceptive deficits may persist after recovery of BN and may be a biological trait that predisposes symptom development in BN. However, no studies to date have directly assessed interoceptive sensitivity, or accuracy in detecting and perceiving internal body cues, in patients with or recovered from BN. Nine women who had recovered from BN and 10 healthy control women completed the Heart Beat Perception Task (HBPT) in which individuals were required to estimate the number of heartbeats between intervals of time. Accuracy scores were compared between groups. Significant differences were found between the groups on the HBPT ((F1,19) = 7.78, p = .013, Cohen's d = 1.16) when controlling for age. These results suggest that deficits in interoceptive sensitivity are present in individuals recovered from BN. Thus interoceptive deficits may be one factor that bridges the gap between brain dysfunction and symptom presentation in BN.
自我报告研究表明，神经性贪食症（BN）患者存在内感受意识困难。事实上，BN 恢复后，内感受缺陷可能仍然存在，并且可能是一种使 BN 症状发展的生物特征。然而，迄今为止，尚无研究直接评估 BN 患者或已康复患者的内感受敏感性或检测和感知内部身体线索的准确性。9 名从 BN 中康复的女性和 10 名健康对照组女性完成了心跳感知任务（HBPT），要求个体在时间间隔之间估计心跳次数。比较了组间的准确率分数。在控制年龄的情况下，HBPT 中两组之间存在显著差异（F1,19 = 7.78，p =.013，Cohen's d = 1.16）。这些结果表明，从 BN 中康复的个体存在内感受敏感性缺陷。因此，内感受缺陷可能是连接 BN 中大脑功能障碍和症状表现之间差距的因素之一。
