Department of Oral Health Sciences, Katholieke Universiteit Leuven and Dentistry, University Hospitals Leuven, Belgium.
J Breath Res. 2013 Dec;7(4):046006. doi: 10.1088/1752-7155/7/4/046006. Epub 2013 Nov 1.
This study aims to analyze the correlation between Solobacterium moorei (S. moorei), both on the tongue and in saliva, and several oral malodour- and clinical parameters. Data from 193 patients visiting a halitosis clinic were used for analysis. A questionnaire assessed their general health, allergies, medication, smoking habits and oral hygiene. Following halitosis parameters were recorded: organoleptic score (OLS) (0-5), total concentration of volatile sulfur compounds (VSC) (Halimeter), individual concentrations of VSC (Oral Chroma), tongue coating (MTCI, WTCI and mWTCI), salivary parameters (flow rate and pH), oral hygiene, tonsil health and periodontal health. In all subjects, microbiological samples were collected from the tongue coating and from the saliva, and a quantitative polymerase chain reaction was performed to detect S. moorei. A significant correlation could be established between S. moorei, from both tongue and saliva, and several breath parameters (OLS, H2S, CH3SH, (CH3)2S and total VSCs), tongue coating indices and periodontal indices (gingivitis, periodontitis and oral hygiene). This study suggests a strong association between the presence of S. moorei and oral malodour (s54747).
本研究旨在分析舌部和唾液中的 Solobacterium moorei（S. moorei）与多种口腔异味和临床参数之间的相关性。研究数据来自于 193 名就诊于口臭诊所的患者。采用问卷调查评估了他们的一般健康状况、过敏史、用药情况、吸烟习惯和口腔卫生状况。记录了以下口臭参数：感官评分（OLS）（0-5）、挥发性硫化合物（VSC）总浓度（Halimeter）、VSC 个体浓度（Oral Chroma）、舌苔（MTCI、WTCI 和 mWTCI）、唾液参数（流速和 pH 值）、口腔卫生状况、扁桃体健康状况和牙周健康状况。在所有受试者中，均从舌部涂层和唾液中采集微生物样本，并进行聚合酶链式反应（PCR）定量检测以检测 S. moorei。结果显示，舌部和唾液中的 S. moorei 与多种呼吸参数（OLS、H2S、CH3SH、(CH3)2S 和总 VSCs）、舌苔指数和牙周指数（牙龈炎、牙周炎和口腔卫生）存在显著相关性。本研究表明，S. moorei 的存在与口腔异味之间存在很强的关联性。
