*Division of HIV/AIDS Prevention, National Centers for HIV, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA; and †ICF International, Atlanta, GA.
J Acquir Immune Defic Syndr. 2014 Mar 1;65(3):350-8. doi: 10.1097/QAI.0000000000000054.
To examine the prevalence of unplanned pregnancies among HIV-infected women in care in the United States.
We used the 2007-2008 cycles of the Medical Monitoring Project, which collected data on HIV-infected adults in care. Women were included if they had an HIV diagnosis before 45 years of age and responded to questions about pregnancies and pregnancy planning after HIV diagnosis. Logistic regression was used to calculate unadjusted and adjusted odds ratios (AORs) and 95% confidence intervals (CIs) for correlates of unplanned pregnancies among women with ≥ 1 pregnancy at or after an HIV diagnosis.
Of 1492 women, 382 (25.6%) reported ≥ 1 pregnancy after HIV diagnosis (median diagnosis age = 25.0 years; interquartile range = 21.0-30.0); 58% were non-Hispanic black, 22% Hispanic, and 15% non-Hispanic white. Of those, 326 (85.3%) reported ≥ 1 unplanned pregnancy; 124 (32.5%) reported recent unprotected vaginal and/or anal sex with a male partner with either negative or unknown HIV status. Unplanned pregnancies were more likely among women who reported nadir CD4 cell counts <200 cells/μL (AOR = 2.3; 95% CI: 1.2 to 4.8) or did not report nadir CD4 cell counts (AOR = 4.3; 95% CI: 1.9 to 10.5) compared with women who reported nadir CD4 cell counts ≥ 200 cells/μL; and who received public assistance in the most recent year before Medical Monitoring Project interview (AOR = 2.1; 95% CI: 1.1 to 3.8) compared with women who did not receive assistance.
Unplanned pregnancies were prevalent among our sample. To avoid unplanned pregnancies, HIV-infected women need access to effective family planning services and risk reduction discussions during routine care visits.
调查美国接受治疗的 HIV 感染者中意外妊娠的流行情况。
我们使用了 2007-2008 年医疗监测项目的数据,该项目收集了接受治疗的 HIV 感染者的成人数据。如果女性在 45 岁之前被诊断出 HIV 感染,并且在 HIV 诊断后对妊娠和妊娠计划问题做出回应,就将其纳入研究。采用 logistic 回归计算调整和未调整比值比(AOR)和 95%置信区间(CI),以评估与 HIV 诊断后至少一次妊娠的女性发生意外妊娠的相关因素。
在 1492 名女性中,382 名(25.6%)报告了 HIV 诊断后至少一次妊娠(中位诊断年龄=25.0 岁;四分位距=21.0-30.0);58%为非西班牙裔黑人,22%为西班牙裔,15%为非西班牙裔白人。其中,326 名(85.3%)报告了至少一次意外妊娠;124 名(32.5%)报告了最近与男性伴侣发生了未使用保护措施的阴道和/或肛门性行为,而男性伴侣的 HIV 状态为阴性或未知。与报告最低 CD4 细胞计数≥200 个/μL 的女性相比,报告最低 CD4 细胞计数<200 个/μL(AOR=2.3;95%CI:1.2 至 4.8)或未报告最低 CD4 细胞计数(AOR=4.3;95%CI:1.9 至 10.5)的女性更有可能发生意外妊娠;与未接受医疗监测项目访谈前一年未接受公共援助的女性相比,最近一年接受公共援助的女性(AOR=2.1;95%CI:1.1 至 3.8)更有可能发生意外妊娠。
在我们的样本中,意外妊娠较为常见。为避免意外妊娠,HIV 感染者需要在常规护理就诊时获得有效的计划生育服务和风险降低讨论。