HIV 阳性育龄妇女中的饮酒行为,美国,2013-2014 年。

Alcohol use among HIV-positive women of childbearing age, United States, 2013-2014.

机构信息

Division of HIV/AIDS Prevention, National Centers for HIV, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention.

Excessive Alcohol Use Prevention Team, National Center for Chronic Disease and Prevention and Health Promotion, Centers for Disease and Prevention.

出版信息

AIDS Care. 2021 Aug;33(8):1024-1036. doi: 10.1080/09540121.2020.1808161. Epub 2020 Aug 18.

Abstract

More than one-quarter of the adults living with diagnosed HIV infection in the US are women. Binge drinking (i.e., ≥4 alcoholic drinks per occasion for women) is associated with poor HIV treatment compliance, HIV incidence, and unplanned pregnancy. However, little is known about the prevalence of binge drinking among women of childbearing age who are living with HIV (WLWH) and health risk behaviours among those who binge drink. Using the 2013-2014 data cycles of Medical Monitoring Project, we assessed the weighted prevalence of drinking patterns by socio-demographic, clinical and reproductive characteristics of 946 WLWH. Logistic regression was used to calculate unadjusted and adjusted prevalence ratios and 95% confidence intervals. Overall, 39% of WLWH reported current drinking and 10% reported binge drinking. Compared to non-drinkers, binge drinkers were less likely to adhere to antiretroviral therapy (ART) or be virally suppressed. In multivariate analyses, binge drinking among WLWH was associated with smoking, drug use, and reduced ART adherence compared to non-drinkers, increasing the likelihood of negative clinical outcomes. WLWH may benefit from a comprehensive approach to reducing binge drinking including alcohol screening and brief interventions and evidence-based policy strategies that could potentially improve adherence to HIV treatment.

摘要

美国超过四分之一的确诊 HIV 感染者为女性。狂饮(即女性每次饮酒≥4 杯)与 HIV 治疗依从性差、HIV 发病率和意外怀孕有关。然而,对于生育年龄的 HIV 感染者(WLWH)中狂饮的流行程度以及狂饮者的健康风险行为知之甚少。利用医疗监测项目 2013-2014 年的数据周期,我们根据 946 名 WLWH 的社会人口统计学、临床和生殖特征评估了饮酒模式的加权流行率。使用逻辑回归计算了未经调整和调整后的患病率比及其 95%置信区间。总体而言,39%的 WLWH 报告目前饮酒,10%报告狂饮。与不饮酒者相比,狂饮者更不可能坚持抗逆转录病毒治疗(ART)或病毒得到抑制。在多变量分析中,与不饮酒者相比,WLWH 中的狂饮与吸烟、吸毒和降低 ART 依从性相关,增加了出现负面临床结局的可能性。WLWH 可能受益于一种综合方法来减少狂饮,包括酒精筛查和简短干预以及基于证据的政策策略,这可能会提高 HIV 治疗的依从性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b09/11000390/688ba1c43bec/nihms-1976944-f0001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索