Nor Faridah Mohd, Pastor Robert F, Schutkowski Holger
Department of Pathology, Universiti Kebangsaan Malaysia Medical Centre (UKMMC), Malaysia
Department of Anthropology, University of Oregon, USA.
Med Sci Law. 2014 Oct;54(4):203-8. doi: 10.1177/0025802413506573. Epub 2013 Nov 4.
Estimation of age from microscopic examination of human bone utilizes bone remodeling. This allows 2 regression equation to be determined in a specific population based on the variation in osteon turnover in different populations. The aim of this study was to provide age estimation for Malaysian males. Ground undecalcified cross sections were prepared from long limb bones of 50 deceased males aged between 21 and 78 years. Ten microstructural parameters were measured and subjected to multivariate regression analysis. Results showed that osteon count had the highest correlation with age (R = 0.43), and age was estimated to be within 10.94 years of the true value in 98% of males. Cross validation of the equation on 50 individuals showed close correspondence of true ages with estimated ages. Further studies are needed to validate and expand these results.
通过对人类骨骼进行显微镜检查来估计年龄利用了骨骼重塑。这使得能够基于不同人群中骨单位更新的差异,在特定人群中确定两个回归方程。本研究的目的是为马来西亚男性提供年龄估计。从50名年龄在21至78岁之间的已故男性的长肢骨制备了未脱钙的磨片横断面。测量了十个微观结构参数并进行了多元回归分析。结果表明,骨单位计数与年龄的相关性最高(R = 0.43),并且在98%的男性中,估计年龄与真实年龄相差在10.94岁以内。对50个人的方程进行交叉验证显示,真实年龄与估计年龄密切对应。需要进一步的研究来验证和扩展这些结果。