Paris Cardiovascular Research Center, Inserm Unit 970, Paris, France.
Circ Arrhythm Electrophysiol. 2013 Dec;6(6):1185-91. doi: 10.1161/CIRCEP.113.000651. Epub 2013 Nov 4.
No specific data are available on characteristics and outcome of sudden cardiac death (SCD) during sport activities among women in the general population.
From a prospective 5-year national survey, involving 820 subjects 10 to 75 years old who presented with SCD (resuscitated or not) during competitive or recreational sport activities, 43 (5.2%) such events occurred in women, principally during jogging, cycling, and swimming. The level of activity at the time of SCD was moderate to vigorous in 35 cases (81.4%). The overall incidence of sport-related SCD, among 15- to 75-year-old women, was estimated as 0.59 (95% confidence interval [CI], 0.39-0.79) to 2.17 (95% CI, 1.38-2.96) per year per million female sports participants for the 80th and 20th percentiles of reporting districts, respectively. Compared with men, the incidence of SCDs in women was dramatically lower, particularly in the 45- to 54-year range (relative risk, 0.033; 95% CI, 0.015-0.075). Despite similar circumstances of occurrence, survival at hospital admission (46.5%; 95% CI, 31.0-60.0) was significantly higher than that for men (30.0%; 95% CI, 26.8-33.2; P=0.02), although this did not reach statistical significance for hospital discharge. Favorable neurological outcomes were similar (80%). Cause of death seemed less likely to be associated with structural heart disease in women compared with men (58.3% versus 95.8%; P=0.003).
Sports-related SCDs in women participants seems dramatically less common (up to 30-fold less frequent) compared with men. Our results also suggest a higher likelihood of successful resuscitation as well as less frequency of structural heart disease in women compared with men.
目前尚无关于普通人群中女性在运动期间发生心源性猝死（SCD）的特征和结局的具体数据。
在一项涉及 820 名年龄在 10 至 75 岁之间的在竞技或娱乐性运动期间发生 SCD（复苏或未复苏）的前瞻性 5 年全国性调查中，43 名（5.2%）此类事件发生在女性中，主要发生在慢跑、骑自行车和游泳时。35 例（81.4%）SCD 发生时活动水平为中等到剧烈。在 15 至 75 岁的女性中，运动相关 SCD 的总发生率估计为每百万女性运动参与者每年为 0.59（95%置信区间[CI]，0.39-0.79）至 2.17（95%CI，1.38-2.96）在报告地区的第 80 和第 20 百分位。与男性相比，女性 SCD 的发生率明显较低，尤其是在 45 至 54 岁年龄组（相对风险，0.033；95%CI，0.015-0.075）。尽管发生情况相似，但女性在入院时的存活率（46.5%；95%CI，31.0-60.0）明显高于男性（30.0%；95%CI，26.8-33.2；P=0.02），尽管这在出院时未达到统计学意义。良好的神经结局相似（80%）。与男性相比，女性死亡原因似乎不太可能与结构性心脏病有关（58.3%比 95.8%；P=0.003）。
与男性相比，女性参与者的运动相关 SCD 似乎明显较少见（低至 30 倍）。我们的结果还表明，女性的复苏成功率更高，且结构性心脏病的发生频率低于男性。
