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同一家族青少年腰椎峡部裂:三例报告并文献复习

Lumbar spondylolysis in juveniles from the same family: a report of three cases and a review of the literature.

作者信息

Yamada Atsuhisa, Sairyo Koichi, Shibuya Isao, Kato Ko, Dezawa Akira, Sakai Toshinori

机构信息

Department of Orthopedic Surgery, Teikyo University Mizonokuchi Hospital, 3-8-3 Mizonokuchi, Takatsu-ku, Kawasaki 213-8507, Japan.

出版信息

Case Rep Orthop. 2013;2013:272514. doi: 10.1155/2013/272514. Epub 2013 Sep 26.

Abstract

Spondylolysis is reported as a stress fracture of the pars interarticularis with a strong hereditary basis. Three cases of lumbar spondylolysis in juveniles from the same family are reported, and the genetics of the condition are reviewed. The first boy, a 13-year-old soccer player, was diagnosed with terminal stage L5 bilateral spondylolysis with grade 1 slippage. The second boy, a 10-year-old baseball player, had terminal stage right side unilateral spondylolysis. The third boy, also a 10-year-old baseball player, was diagnosed with early stage bilateral L5 spondylolysis. The second and third boys are identical twins, and all three cases exhibited concomitant spina bifida occulta. Lumbar spondylolysis has a strong hereditary basis and is reported to be an autosomal dominant condition.

摘要

峡部裂被认为是关节突间部的应力性骨折,具有很强的遗传基础。本文报告了来自同一家庭的3例青少年腰椎峡部裂病例,并对该病的遗传学进行了综述。第一个男孩,13岁,足球运动员,被诊断为终末期L5双侧峡部裂伴1级滑脱。第二个男孩,10岁,棒球运动员,患有终末期右侧单侧峡部裂。第三个男孩,也是10岁的棒球运动员,被诊断为早期双侧L5峡部裂。第二个和第三个男孩是同卵双胞胎,所有3例均伴有隐性脊柱裂。腰椎峡部裂有很强的遗传基础,据报道是一种常染色体显性疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05f8/3803119/7f890a98770b/CRIM.ORTHOPEDICS2013-272514.001.jpg

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