Nowacki P, Fryze C, Wichert K
Folia Haematol Int Mag Klin Morphol Blutforsch. 1985;112(6):879-85.
In 35 cases out of 37 (88%) microthrombi have been found in CNS. They appeared much more frequently than it could be expected on the basis of the clinical picture of DIC syndrome or changes in the coagulation system. Microthrombi occurred prevalently in white substance of the frontal and occipital lobes as well as in thalamus. In 15 cases the microthrombi were the only evidence of DIC syndrome, besides clinically "mute" one. It should be emphasized that almost in half of the cases we encountered numerous disseminated microthrombi in many regions of CNS. Unequal distribution of microthrombi in CNS points out the significance of the local factor in the pathogenesis of DIC syndrome.
在37例中有35例（88%）在中枢神经系统中发现了微血栓。它们出现的频率比根据弥散性血管内凝血（DIC）综合征的临床表现或凝血系统变化所预期的要高得多。微血栓主要出现在额叶和枕叶的白质以及丘脑。在15例中，微血栓是DIC综合征的唯一证据，临床症状不明显。应该强调的是，几乎在一半的病例中，我们在中枢神经系统的许多区域发现了大量弥散性微血栓。中枢神经系统中微血栓分布不均表明局部因素在DIC综合征发病机制中的重要性。
