Ignatowicz R, Ignatowica L, Jaremko A, Gdakowicz B, Kowalczyk K
Neurol Neurochir Pol. 1975 Sep-Oct;9(5):617-9.
The authors present their observations on treatment with Noveril of nocturnal enuresis in 49 children aged from 6 to 16 years. The drug is a derivative of dibenzodiazepine belonging to the group of thymoleptic agents with an action similar to that of imipramine. Noveril was given in doses from 20 to 100 mg daily during 3 to 9 weeks. In the final evaluation of the drug the frequency of enuresis before, during and after treatment was taken into account. In 25 cases an improvement was observed, usually in psychogenic nocturnal enuresis. Side effects included oral dryness, headaches and dizziness, and sleep disturbances observed in 4 cases. The tolerance of the drug was good. Noveril has a favourable effect in children with nocturnal enuresis, particularly of psychogenic origin.
作者介绍了他们对49名6至16岁儿童使用诺凡里尔治疗夜间遗尿症的观察结果。该药物是二苯并二氮䓬的衍生物，属于心境稳定剂类，其作用与丙咪嗪相似。诺凡里尔的给药剂量为每日20至100毫克，疗程为3至9周。在对该药物的最终评估中，考虑了治疗前、治疗期间和治疗后的遗尿频率。在25例病例中观察到病情有所改善，通常是对心因性夜间遗尿症有效。副作用包括口干、头痛、头晕，4例出现睡眠障碍。该药物耐受性良好。诺凡里尔对夜间遗尿症儿童，尤其是心因性遗尿症儿童有良好疗效。
