Visscher A P, Lam T J, Hart N, Felt-Bersma R J F
Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands,
Int Urogynecol J. 2014 May;25(5):607-13. doi: 10.1007/s00192-013-2238-0. Epub 2013 Nov 7.
Our aim was to evaluate alterations in anorectal function after anal sphincteroplasty for third-degree obstetric anal sphincter injury (OASI) in relation to clinical outcome.
In this retrospective, descriptive, cross-sectional study conducted between 1998 and 2008, women with persisting fecal incontinence (FI) after 3a OASI and all women with grade 3b or 3c OASI were sent for anorectal function evaluation (AFE) consisting of anal manometry and endosonography 3 months after sphincteroplasty. In 2011, questionnaires regarding FI (Vaizey/Wexner), urinary incontinence (UI) [International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF)], sexual function [Female Sexual Function Index (FSFI)], and quality of life (QOL) (Rand-36) were sent and women were asked to undergo additional AFE.
Sixty-six women underwent AFE. Mean follow-up was 5.0 years. Forty (61%) patients returned questionnaires regarding FI and UI. Prevalence of FI was 63% flatus, 50% liquid stool, and 20% solid stool. Thirty-two of 40 also reported on QOL and SF. Sexual dysfunction was present in the majority of women (cutoff value 26.55) and more pronounced in larger OASI. Sixteen of 40 women underwent additional AFE. Women with combined internal (IAS) and external (EAS) anal sphincter injury (n = 6) had worse FI (P < 0.050) and lower anal pressures (P = 0.040) than women with isolated EAS injury (n = 10).
Follow-up after third-degree OASI suggests poor anorectal and sexual function. Women with combined external and internal OASI show more deterioration in anorectal function and experience worse FI. Therefore, special attention should be paid to these women in order to mitigate these symptoms later in life.
我们的目的是评估三度产科肛门括约肌损伤(OASI)行肛门括约肌成形术后肛门直肠功能的改变及其与临床结局的关系。
在这项于1998年至2008年间开展的回顾性、描述性横断面研究中,三度OASI后仍存在大便失禁(FI)的女性以及所有3b级或3c级OASI女性在括约肌成形术后3个月接受了包括肛门测压和腔内超声检查的肛门直肠功能评估(AFE)。2011年,发放了关于FI(Vaizey/Wexner量表)、尿失禁(UI)[国际尿失禁咨询问卷简表(ICIQ-SF)]、性功能[女性性功能指数(FSFI)]和生活质量(QOL)(兰德36项健康调查量表)的问卷,并要求女性接受额外的AFE。
66名女性接受了AFE。平均随访时间为5.0年。40名(61%)患者返回了关于FI和UI的问卷。FI的发生率为:排气时63%,稀便时50%,固体粪便时20%。40名患者中的32名还报告了生活质量和性功能。大多数女性存在性功能障碍(临界值为26.55),且在较大程度的OASI中更为明显。40名女性中的16名接受了额外的AFE。合并内括约肌(IAS)和外括约肌(EAS)损伤的女性(n = 6)比单纯EAS损伤的女性(n = 10)有更严重的FI(P < 0.050)和更低的肛门压力(P = 0.040)。
三度OASI后的随访显示肛门直肠和性功能较差。合并外括约肌和内括约肌损伤的女性肛门直肠功能恶化更明显,且FI更严重。因此,应特别关注这些女性,以便在其晚年减轻这些症状。