Health Effects Research Laboratory, MD-51A, US Environmental Protection Agency, 27711, Research Triangle Park, NC, USA.
Environ Geochem Health. 1992 Jun;14(2):63-8. doi: 10.1007/BF01783631.
Research needed to resolve the uncertainties of cancer risk from ingestion of arsenic in drinking water is described. The recommendations fall into two categories reflecting the areas of greatest uncertainty regarding the assessment of arsenic risk: research on the mechanism of cancer, and research on the metabolism and detoxification of arsenic. The recommendations are discussed in light of risk assessment and risk management issues, stressing the need for scientists to interpret research findings for decision managers.
本文描述了为解决饮用水中砷摄入致癌风险的不确定性所需开展的研究。这些建议可分为两类,反映了在评估砷风险方面最不确定的两个领域:癌症发生机制的研究,以及砷代谢和解毒的研究。本文根据风险评估和风险管理问题对这些建议进行了讨论,强调了科学家有必要为决策管理人员解释研究结果。