Koch Sonja, Quadflieg Norbert, Fichter Manfred
Department of Psychiatry, University of Munich (LMU), Nussbaumstr. 7, 80336, Munich, Germany,
Eat Weight Disord. 2014 Mar;19(1):21-9. doi: 10.1007/s40519-013-0082-3. Epub 2013 Nov 7.
With data from the Christina-Barz-Study, we report mortality rates and predictors of death in purging disorder (PurD) as well as additional information concerning the fatal cases.
The study was conducted with 225 consecutively admitted inpatients during the years 1999-2005. About 9 years later, fatal cases were identified by local registration office records. The standardised mortality ratio (SMR) was calculated through mortality tables of the Federal Office of Statistics, Germany. To identify predictors of death, survival analyses were performed. Spouses, relatives or doctors of the deceased were consulted by interview or questionnaire for further information of pathogenesis and circumstances of death.
Six of the 225 sample individuals could not be located for the follow-up. Eleven of 219 former inpatients had died during the follow-up interval. The crude mortality rate was 5.0%. The SMR was 3.90 [95% confidence interval (2.05; 7.21)]. Age at admission and presence of one or more co-morbid somatic illnesses at admission were factors associated with a shorter time period until death.
Our data indicate that there is a higher number of deaths within the study population than expected. Paying particular attention to age and the severity of co-morbid somatic symptoms could improve the outcome of patients with PurD.
利用克里斯蒂娜 - 巴兹研究的数据，我们报告了清除障碍（PurD）的死亡率和死亡预测因素，以及有关致命病例的其他信息。
该研究对1999年至2005年间连续收治的225名住院患者进行。约9年后，通过当地户籍登记处记录确定致命病例。标准化死亡率（SMR）通过德国联邦统计局的死亡率表计算得出。为了确定死亡预测因素，进行了生存分析。通过访谈或问卷调查咨询死者的配偶、亲属或医生，以获取有关发病机制和死亡情况的更多信息。
225名样本个体中有6名无法找到进行随访。219名 former inpatients（原文此处有误，推测为former inpatients，意为“ former inpatients”）中有11名在随访期间死亡。粗死亡率为5.0%。标准化死亡率为3.90 [95%置信区间（2.05；7.21）]。入院时的年龄以及入院时存在一种或多种共病躯体疾病是与死亡时间较短相关的因素。
我们的数据表明，研究人群中的死亡人数高于预期。特别关注年龄和共病躯体症状的严重程度可能会改善PurD患者的预后。
