Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University (LMU), Munich, Germany.
Schön Klinik Roseneck affiliated with the Medical Faculty of the University of Munich (LMU), Prien, Germany.
Int J Eat Disord. 2019 Dec;52(12):1365-1369. doi: 10.1002/eat.23135. Epub 2019 Jul 10.
To report on the long-term mortality of eating disorders in male inpatients.
Crude mortality rates (CMR) and standardized mortality ratios (SMR) were computed for a large sample of males (147 anorexia nervosa [AN], 81 bulimia nervosa [BN], 110 eating disorder not otherwise specified [ED-NOS]; DSM-IV). In addition, a survival analysis from onset of eating disorder to death or end of observation was computed.
CMR was 12.9% in AN, 11.1% in BN, and 6.4% in ED-NOS. Standardized mortality was significantly elevated in males with AN (SMR = 5.91; 95% confidence interval 3.56-9.23) as well as ED-NOS (SMR = 3.40; 95% confidence interval 1.37-7.01) but not in males with BN (SMR = 1.88; 95% confidence interval 0.86-3.58). Males with AN died sooner after onset of eating disorder than males with BN or ED-NOS.
Mortality in male inpatients with eating disorder is high, especially in AN. There is need for developing more effective treatments to achieve better outcome.
报告男性住院患者进食障碍的长期死亡率。
对大量男性（147 例神经性厌食症[AN]，81 例神经性贪食症[BN]，110 例未特定进食障碍[ED-NOS]；DSM-IV）进行了粗死亡率（CMR）和标准化死亡率比（SMR）的计算。此外，还计算了从进食障碍发病到死亡或观察结束的生存分析。
AN 的 CMR 为 12.9%，BN 为 11.1%，ED-NOS 为 6.4%。AN（SMR=5.91；95%置信区间 3.56-9.23）和 ED-NOS（SMR=3.40；95%置信区间 1.37-7.01）的男性标准化死亡率显著升高，但 BN 男性的标准化死亡率没有升高（SMR=1.88；95%置信区间 0.86-3.58）。AN 患者发病后死亡时间早于 BN 或 ED-NOS 患者。
进食障碍男性住院患者的死亡率很高，尤其是 AN。需要开发更有效的治疗方法以获得更好的结果。
