男性进食障碍治疗后的死亡率：一项大型前瞻性研究。

Mortality in males treated for an eating disorder-A large prospective study.

机构信息

Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University (LMU), Munich, Germany.

Schön Klinik Roseneck affiliated with the Medical Faculty of the University of Munich (LMU), Prien, Germany.

出版信息

Int J Eat Disord. 2019 Dec;52(12):1365-1369. doi: 10.1002/eat.23135. Epub 2019 Jul 10.

DOI:10.1002/eat.23135

PMID:31291032

Abstract

OBJECTIVE

To report on the long-term mortality of eating disorders in male inpatients.

METHOD

Crude mortality rates (CMR) and standardized mortality ratios (SMR) were computed for a large sample of males (147 anorexia nervosa [AN], 81 bulimia nervosa [BN], 110 eating disorder not otherwise specified [ED-NOS]; DSM-IV). In addition, a survival analysis from onset of eating disorder to death or end of observation was computed.

RESULTS

CMR was 12.9% in AN, 11.1% in BN, and 6.4% in ED-NOS. Standardized mortality was significantly elevated in males with AN (SMR = 5.91; 95% confidence interval 3.56-9.23) as well as ED-NOS (SMR = 3.40; 95% confidence interval 1.37-7.01) but not in males with BN (SMR = 1.88; 95% confidence interval 0.86-3.58). Males with AN died sooner after onset of eating disorder than males with BN or ED-NOS.

DISCUSSION

Mortality in male inpatients with eating disorder is high, especially in AN. There is need for developing more effective treatments to achieve better outcome.

摘要

目的

报告男性住院患者进食障碍的长期死亡率。

方法

对大量男性（147 例神经性厌食症[AN]，81 例神经性贪食症[BN]，110 例未特定进食障碍[ED-NOS]；DSM-IV）进行了粗死亡率（CMR）和标准化死亡率比（SMR）的计算。此外，还计算了从进食障碍发病到死亡或观察结束的生存分析。

结果

AN 的 CMR 为 12.9%，BN 为 11.1%，ED-NOS 为 6.4%。AN（SMR=5.91；95%置信区间 3.56-9.23）和 ED-NOS（SMR=3.40；95%置信区间 1.37-7.01）的男性标准化死亡率显著升高，但 BN 男性的标准化死亡率没有升高（SMR=1.88；95%置信区间 0.86-3.58）。AN 患者发病后死亡时间早于 BN 或 ED-NOS 患者。