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[鹅掌柴属植物化学成分及药理活性研究进展]

[Advances of chemical constituents and pharmacological activities of schefflera genus].

作者信息

Wang Yan, Chen Ruo-Yun, Yu De-Quan

机构信息

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2013 Jul;38(14):2254-63.

Abstract

The genus Schefflera (Araliaceae) consists of 1100 species, 35 of which can be found in China. Some species of the genus have been used in traditional medicine to treat rheumatalgia, trauma, fracture, headache, and so on. Phytochemical studies of the genus have demonstrated the presence of large number of triterpenoids and their saponins, along with some long-chain compounds, steroids and sesquiterpenes. Furthermore, many pharmacological activities of the genus such as anti-inflammatory, anticancer and antiviral activities have been reported. In this article, new development of constituents and biological activities of Schefflera genus is reviewed and summarized for its further development and utilization.

摘要

鹅掌柴属(五加科)有1100个物种,其中35种在中国可以找到。该属的一些物种已被用于传统医学,以治疗风湿痛、创伤、骨折、头痛等。对该属的植物化学研究表明,存在大量的三萜类化合物及其皂苷,以及一些长链化合物、甾体和倍半萜。此外,该属的许多药理活性,如抗炎、抗癌和抗病毒活性也有报道。本文对鹅掌柴属植物的成分和生物活性的新进展进行了综述和总结,以便其进一步开发利用。

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