Basset-Seguin N
Service de Dermatologie, Hôpital Saint Louis, 1 avenue Claude Vellefaux 75475 Paris cedex 10, France.
Ann Dermatol Venereol. 2013 Nov;140 Suppl 2:223-8. doi: 10.1016/S0151-9638(13)70138-8.
Photodynamic therapy (PDT) combines the use of a topical sensitizer and its excitation with a light of appropriate wavelength. Its use in dermatooncology has been possible in France in 2006 when the methyl ester ALA or Metvixia® got approved.
To provide a panoramic view of validated indications of PDT in oncodermatology.
This work is based on the review of the literature as well as available guidelines or recommendation on PDT in dermatology.
Standardized protocols and results of the main clinical trials are given for the three major indications in dermatology: actinic keratosis, basal cell carcinoma and Bowen disease.
PDT has its role to play in the treatment of multiple superficial carcinomas and cutaneous precancerous lesions and its main advantage resides in its optimal healing.
光动力疗法（PDT）结合了局部致敏剂的使用及其与适当波长光的激发。2006年，当甲基酯ALA或Metvixia®获得批准后，它在法国的皮肤肿瘤学中得以应用。
全面介绍光动力疗法在肿瘤皮肤病学中的有效适应证。
这项工作基于对文献以及皮肤病学中光动力疗法的现有指南或建议的综述。
给出了皮肤科三大主要适应证（光化性角化病、基底细胞癌和鲍恩病）的标准化方案和主要临床试验结果。
光动力疗法在多种浅表癌和皮肤癌前病变的治疗中发挥着作用，其主要优势在于愈合效果最佳。
