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挤压综合征:一例病例报告及文献综述

Crush syndrome: a case report and review of the literature.

作者信息

Genthon Alissa, Wilcox Susan R

机构信息

Department of Emergency Medicine, Brigham and Women's Hospital, Boston, Massachusetts; Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts.

Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts; Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts.

出版信息

J Emerg Med. 2014 Feb;46(2):313-9. doi: 10.1016/j.jemermed.2013.08.052. Epub 2013 Nov 5.

DOI:10.1016/j.jemermed.2013.08.052
PMID:24199724
Abstract

BACKGROUND

Crush trauma to the extremities, even if not involving vital organs, can be life threatening. Crush syndrome, the systemic manifestation of the breakdown of muscle cells with release of contents into the circulation, leads to metabolic derangement and acute kidney injury. Although common in disaster scenarios, emergency physicians also see the syndrome in patients after motor-vehicle collisions and patients "found down" due to intoxication.

OBJECTIVE

The objectives of this review are to discuss the pathophysiology of crush syndrome, report on prehospital and emergency department treatment, and discuss the relationship between crush syndrome and compartment syndrome.

DISCUSSION

We present the case of a young man found down after an episode of intoxication, with compartment syndrome of his lower extremity and crush syndrome. Although he eventually required an amputation, aggressive fluid resuscitation prevented further kidney injury and metabolic derangement.

CONCLUSIONS

Early, aggressive resuscitation in the prehospital setting, before extrication if possible, is recommended to reduce the complications of crush syndrome. Providers must be aware of the risk of hyperkalemia shortly after extrication. Ongoing resuscitation with i.v. fluids is the mainstay of treatment. Compartment syndrome is a common complication, and prompt fasciotomies should be performed when compartment syndrome is present.

摘要

背景

肢体挤压伤即使未累及重要器官,也可能危及生命。挤压综合征是肌肉细胞破裂并将内容物释放到循环系统中的全身性表现,可导致代谢紊乱和急性肾损伤。虽然在灾难场景中很常见,但急诊医生在机动车碰撞后的患者以及因中毒而“倒地”的患者中也会见到该综合征。

目的

本综述的目的是讨论挤压综合征的病理生理学,报告院前和急诊科的治疗情况,并讨论挤压综合征与骨筋膜室综合征之间的关系。

讨论

我们报告了一名年轻男子在一次中毒事件后被发现倒地的病例,他患有下肢骨筋膜室综合征和挤压综合征。尽管他最终需要截肢,但积极的液体复苏防止了进一步的肾损伤和代谢紊乱。

结论

建议在院前环境中尽早进行积极复苏,如有可能在解救前进行,以减少挤压综合征的并发症。施救者必须意识到解救后不久出现高钾血症的风险。持续静脉补液是治疗的主要方法。骨筋膜室综合征是一种常见并发症,当出现骨筋膜室综合征时应及时进行筋膜切开术。

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