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孤立性股浅动脉退行性动脉瘤的外科治疗。

Surgical management of isolated superficial femoral artery degenerative aneurysms.

机构信息

Section of Vascular Surgery, Department of Surgery, University Hospital of Parma, Parma, Italy; Division of Vascular Surgery, Graduate School of Medicine, University of Nice-Sophia-Antipolis, Nice, France.

Division of Vascular Surgery, Graduate School of Medicine, University of Nice-Sophia-Antipolis, Nice, France.

出版信息

J Vasc Surg. 2014 Jan;59(1):152-8. doi: 10.1016/j.jvs.2013.07.011. Epub 2013 Nov 5.

Abstract

OBJECTIVE

To investigate the mode of presentation, diagnosis, association with other aneurysms, operative management, and outcomes of superficial femoral artery (SFA) aneurysms.

METHODS

Records of all patients who underwent surgery for isolated, true SFA aneurysms (not due to infection, vasculitis, or tissue disorders) from 2002 to 2012 in two European centers were retrospectively analyzed. Demographic (sex, age), clinical (cardiovascular risk factors, location of the aneurysm, symptoms, presentation, emergency setting), surgical and radiological data (diameter, surgical technique, runoff vessels patency, presence of aneurysms elsewhere) were obtained for analysis. Follow-up was undertaken with clinical and ultrasound examinations at 1 month, 3 months, 6 months, 12 months, and yearly thereafter. The patency of the graft and the status of the anastomoses and inflow and outflow vessels were assessed. Main end points were represented by 30 days and long-term mortality and amputation-free survival.

RESULTS

A total of 27 cases of SFA aneurysm were analyzed. Mean age at operation was 78 years ± 8.5. At presentation, SFA aneurysms were often symptomatic (rupture was present in 7/27 cases and acute distal ischemia in 6/27 cases), large (mean diameter, 54 mm ± 33.1 mm), bilateral (38% of the cases), and associated with aneurysms elsewhere (84%). Sixteen patients underwent resection of the aneurysm and polytetrafluoroethylene interposition graft, seven patients exclusion of the aneurysm with a femoropopliteal bypass (autogenous bypass in five cases, prosthetic in two), three patients simple ligation, and one patient underwent primary amputation. Mean follow-up was 41.47 months (range, 0.43-128.67 months). Early (<30 days) mortality and amputation rate were 4% and 7%, respectively. Estimated 5-year survival, limb salvage, and graft patency rates were 62%, 88%, and 85%, respectively.

CONCLUSIONS

Degenerative aneurysms of the SFA display peculiar characteristics (in terms of clinical onset, diagnostic timing, and clinical behavior) so that they differ from other peripheral aneurysms. In fact, they often grow to reach a considerable diameter before medical attention is sought, presenting with rupture or ischemia at diagnosis. SFA aneurysms preferentially affect elderly men and are often associated with aneurysms elsewhere. However, despite their rarity, the treatment is usually feasible, and long-term outcomes are good.

摘要

目的

探讨股浅动脉(SFA)动脉瘤的临床表现、诊断、与其他动脉瘤的关系、手术治疗方法及转归。

方法

回顾性分析 2002 年至 2012 年期间在欧洲两个中心因孤立性、真性 SFA 动脉瘤(非感染、脉管炎或组织疾病所致)而接受手术治疗的所有患者的病历资料。分析患者的人口统计学(性别、年龄)、临床(心血管危险因素、动脉瘤位置、症状、表现、急诊情况)、手术和影像学资料(直径、手术技术、流出道血管通畅情况、其他部位的动脉瘤)。通过术后 1 个月、3 个月、6 个月、12 个月及之后每年进行临床和超声检查进行随访。评估移植物通畅情况和吻合口及流入和流出血管的状态。主要终点是 30 天内和长期死亡率以及无截肢生存率。

结果

共分析了 27 例 SFA 动脉瘤患者。手术时的平均年龄为 78 岁±8.5 岁。就诊时,SFA 动脉瘤常伴有症状(破裂 7/27 例,急性远端缺血 6/27 例),瘤体较大(平均直径 54mm±33.1mm),多为双侧(38%的病例),并伴有其他部位的动脉瘤(84%)。16 例患者行动脉瘤切除和聚四氟乙烯间置移植术,7 例行动脉瘤切除伴股腘旁路(自体旁路 5 例,人工旁路 2 例),3 例行单纯结扎术,1 例行一期截肢术。平均随访时间为 41.47 个月(0.43-128.67 个月)。早期(<30 天)死亡率和截肢率分别为 4%和 7%。估计 5 年生存率、肢体存活率和移植物通畅率分别为 62%、88%和 85%。

结论

SFA 退行性动脉瘤在临床表现、诊断时机和临床行为方面具有独特的特征,与其他外周动脉瘤不同。事实上,它们在引起医疗关注之前常常会生长到相当大的直径,然后才出现破裂或缺血性症状。SFA 动脉瘤多发生于老年男性,常伴有其他部位的动脉瘤。然而,尽管其发病率较低,但治疗通常是可行的,长期预后良好。

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