Shimizu Yukie, Tha Khin Khin, Iguchi Akihiro, Cho Yuko, Yoshida Atsushi, Fujima Noriyuki, Tsukahara Akiko, Shirato Hiroki, Terae Satoshi
Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital; Kita-ku, Sapporo, Japan -
Neuroradiol J. 2013 Oct;26(5):514-9. doi: 10.1177/197140091302600504. Epub 2013 Nov 7.
Posterior reversible encephalopathy syndrome (PRES) is characterized by reversible vasogenic edema affecting the subcortical white matter of bilateral occipital and parietal lobes. We describe a case of isolated posterior fossa involvement of PRES which occurred during remission induction chemotherapy for T-cell acute lymphoblastic leukemia. Both the brainstem and cerebellum were extensively involved, but the supratentorial structures were completely spared. The follow-up magnetic resonance images revealed reversibility of most lesions. The knowledge of atypical radiological features of PRES is essential for prompt diagnosis.
后部可逆性脑病综合征(PRES)的特征是双侧枕叶和顶叶皮质下白质出现可逆性血管源性水肿。我们描述了一例在T细胞急性淋巴细胞白血病缓解诱导化疗期间发生的孤立性后颅窝受累的PRES病例。脑干和小脑均广泛受累,但幕上结构完全未受累。随访磁共振成像显示大多数病变具有可逆性。了解PRES的非典型影像学特征对于及时诊断至关重要。