CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Instituto Salud Carlos III, Madrid, Spain.
BMC Psychiatry. 2013 Nov 7;13:285. doi: 10.1186/1471-244X-13-285.
With the imminent publication of the new edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), there has been a growing interest in the study of the boundaries across the three bulimic spectrum syndromes [bulimia nervosa-purging type (BN-P), bulimia nervosa-non purging type (BN-NP) and binge eating disorder (BED)]. Therefore, the aims of this study were to determine differences in treatment response and dropout rates following Cognitive Behavioural Therapy (CBT) across the three bulimic-spectrum syndromes.
The sample comprised of 454 females (87 BED, 327 BN-P and 40 BN-NP) diagnosed according to DSM-IV-TR criteria who were treated with 22 weekly outpatient sessions of group CBT therapy. Patients were assessed before and after treatment using a food and binging/purging diary and some clinical questionnaires in the field of ED. "Full remission" was defined as total absence of binging and purging (laxatives and/or vomiting) behaviors and psychological improvement for at least 4 (consecutive).
Full remission rate was found to be significantly higher in BED (69.5%) than in both BN-P (p < 0.005) and BN-NP (p < 0.001), which presented no significant differences between them (30.9% and 35.5%). The rate of dropout from group CBT was also higher in BED (33.7%) than in BN-P (p < 0.001) and BN-NP (p < 0.05), which were similar (15.4% and 12.8%, respectively).
Results suggest that purging and non-purging BN have similar treatment response and dropping out rates, whereas BED appears as a separate diagnosis with better outcome for those who complete treatment. The results support the proposed new DSM-5 classification.
随着新版《精神障碍诊断与统计手册》(DSM-5)的即将出版,人们对三种贪食症谱综合征[神经性贪食症-清泻型(BN-P)、神经性贪食症-非清泻型(BN-NP)和暴食障碍(BED)]的边界研究产生了浓厚的兴趣。因此,本研究的目的是确定在三种贪食症谱综合征中,认知行为疗法(CBT)治疗后的反应和脱落率差异。
该样本包括 454 名女性(87 名 BED、327 名 BN-P 和 40 名 BN-NP),根据 DSM-IV-TR 标准诊断,接受 22 周的门诊团体 CBT 治疗。患者在治疗前后使用饮食和暴食/清泻日记以及 ED 领域的一些临床问卷进行评估。“完全缓解”定义为完全没有暴食和清泻(泻药和/或呕吐)行为,且心理状态至少改善 4 个(连续)月。
BED 的完全缓解率(69.5%)明显高于 BN-P(p<0.005)和 BN-NP(p<0.001),但后两者之间无显著差异(分别为 30.9%和 35.5%)。BED 的团体 CBT 脱落率(33.7%)也高于 BN-P(p<0.001)和 BN-NP(p<0.05),但后两者相似(分别为 15.4%和 12.8%)。
结果表明,BN-P 和 BN-NP 具有相似的治疗反应和脱落率,而 BED 似乎是一种单独的诊断,对于完成治疗的患者具有更好的结果。研究结果支持 DSM-5 的新分类。