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神经性贪食症和暴饮暴食的心理治疗

Psychological treatments for bulimia nervosa and binging.

作者信息

Hay Phillipa Pj, Bacaltchuk Josué, Stefano Sergio, Kashyap Priyanka

机构信息

Mental Health School of Medicine, Building 3, Campbelltown Campus University of Western Sydney, Locked Bag 1797, Penrith South, New South Wales, Australia, 2570.

出版信息

Cochrane Database Syst Rev. 2009 Oct 7;2009(4):CD000562. doi: 10.1002/14651858.CD000562.pub3.

Abstract

BACKGROUND

A specific manual-based form of cognitive behavioural therapy (CBT) has been developed for the treatment of bulimia nervosa (CBT-BN) and other common related syndromes such as binge eating disorder. Other psychotherapies and modifications of CBT are also used.

OBJECTIVES

To evaluate the efficacy of CBT, CBT-BN and other psychotherapies in the treatment of adults with bulimia nervosa or related syndromes of recurrent binge eating.

SEARCH STRATEGY

Handsearch of The International Journal of Eating Disorders since first issue; database searches of MEDLINE, EXTRAMED, EMBASE, PsycInfo, CURRENT CONTENTS, LILACS, SCISEARCH, CENTRAL and the The Cochrane Collaboration Depression, Anxiety & Neurosis Controlled Trials Register; citation list searching and personal approaches to authors were used. Search date June 2007.

SELECTION CRITERIA

Randomised controlled trials of psychotherapy for adults with bulimia nervosa, binge eating disorder and/or eating disorder not otherwise specified (EDNOS) of a bulimic type which applied a standardised outcome methodology and had less than 50% drop-out rate.

DATA COLLECTION AND ANALYSIS

Data were analysed using the Review Manager software program. Relative risks were calculated for binary outcome data. Standardised mean differences were calculated for continuous variable outcome data. A random effects model was applied.

MAIN RESULTS

48 studies (n = 3054 participants) were included. The review supported the efficacy of CBT and particularly CBT-BN in the treatment of people with bulimia nervosa and also (but less strongly due to the small number of trials) related eating disorder syndromes.Other psychotherapies were also efficacious, particularly interpersonal psychotherapy in the longer-term. Self-help approaches that used highly structured CBT treatment manuals were promising. Exposure and Response Prevention did not enhance the efficacy of CBT.Psychotherapy alone is unlikely to reduce or change body weight in people with bulimia nervosa or similar eating disorders.

AUTHORS' CONCLUSIONS: There is a small body of evidence for the efficacy of CBT in bulimia nervosa and similar syndromes, but the quality of trials is very variable and sample sizes are often small. More and larger trials are needed, particularly for binge eating disorder and other EDNOS syndromes. There is a need to develop more efficacious therapies for those with both a weight and an eating disorder.

摘要

背景

已开发出一种基于手册的特定形式的认知行为疗法(CBT)用于治疗神经性贪食症(CBT-BN)及其他常见相关综合征,如暴饮暴食症。也会使用其他心理疗法及CBT的改良方法。

目的

评估CBT、CBT-BN及其他心理疗法在治疗患有神经性贪食症或复发性暴饮暴食相关综合征的成年人中的疗效。

检索策略

自第一期起手工检索《国际进食障碍杂志》;对MEDLINE、EXTRAMED、EMBASE、PsycInfo、《现刊目次》、LILACS、SCISEARCH、CENTRAL以及Cochrane协作网抑郁、焦虑与神经症对照试验注册库进行数据库检索;使用引文列表检索及向作者个人咨询的方法。检索日期为2007年6月。

入选标准

针对患有神经性贪食症、暴饮暴食症和/或未另行规定的贪食型进食障碍(EDNOS)的成年人进行心理治疗的随机对照试验,试验采用标准化结局方法且脱落率低于50%。

数据收集与分析

使用Review Manager软件程序分析数据。计算二分类结局数据的相对风险。计算连续变量结局数据的标准化均数差值。应用随机效应模型。

主要结果

纳入48项研究(n = 3054名参与者)。该综述支持CBT尤其是CBT-BN在治疗神经性贪食症患者中的疗效,对于相关进食障碍综合征也有疗效(但由于试验数量较少,支持力度较弱)。其他心理疗法也有效,尤其是长期的人际心理治疗。使用高度结构化CBT治疗手册的自助方法很有前景。暴露与反应阻止法并未增强CBT的疗效。单纯心理治疗不太可能减轻或改变神经性贪食症或类似进食障碍患者的体重。

作者结论

有少量证据支持CBT在神经性贪食症及类似综合征中的疗效,但试验质量差异很大且样本量往往较小。需要更多且规模更大的试验,尤其是针对暴饮暴食症和其他EDNOS综合征。有必要为同时患有体重问题和进食障碍的患者开发更有效的疗法。

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