Tröbs R B, Mahnke P F
Zentralbl Allg Pathol. 1985;130(5):397-405.
The development of several cell types was studied in human extrahepatic bile ducts of 5 fetuses, 11 newborn infants (gestational age of 28 to 41 weeks), and 3 children younger than 6 years by means of histological and histochemical staining reactions. Barrel-shaped columnar cells and rod-shaped cells in the mucosa are well described in the literature. Goblet cells are only known at the region of the ampulla of Vater. In our study, goblet cells were found in all cases of newborn infants older than 28 gestational weeks. The cytoplasm of the goblet cells contains a mixture of neutral, carboxylated, and sulphated mucopolysaccharides. The physiological importance of the goblet cells is discussed. Parallels to the development and pathology of gall bladder epithelium are elucidated.
通过组织学和组织化学染色反应，对5例胎儿、11例新生儿（胎龄28至41周）和3例6岁以下儿童的肝外胆管中的几种细胞类型的发育进行了研究。文献中对黏膜中的桶状柱状细胞和杆状细胞已有充分描述。杯状细胞仅在 Vater壶腹区域为人所知。在我们的研究中，在所有胎龄大于28周的新生儿病例中均发现了杯状细胞。杯状细胞的细胞质中含有中性、羧化和硫酸化粘多糖的混合物。讨论了杯状细胞的生理重要性。阐明了与胆囊上皮发育和病理学的相似之处。
